Dixie-Lee Shurland

A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans

Clark, Scott G., Shurland, Dixie-Lee, Meyerowitz, Elliot M., Bargmann, Cornelia I., Van Der Bliek, Alexander M.

Drosophila shibire and its mammalian homologue dynamin regulate an early step in endocytosis. We identified a Caenorhabditis elegans dynamin gene, dyn-1, based upon hybridization to the Drosophila...

Contribution of the GTPase Domain to the Subcellular Localization of Dynamin in the Nematode Caenorhabditis elegans

Labrousse, Arnaud M., Shurland, Dixie-Lee, Van Der Bliek, Alexander M.

Caenorhabditis elegans dynamin is expressed at high levels in neurons and at lower levels in other cell types, consistent with the important role that dynamin plays in the recycling of synaptic...

Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Smirnova, Elena, Griparic, Lorena, Shurland, Dixie-Lee, Van Der Bliek, Alexander M.

Mutations in the human dynamin-related protein Drp1 cause mitochondria to form perinuclear clusters. We show here that these mitochondrial clusters consist of highly interconnected mitochondrial...

A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans

Clark, Scott G., Shurland, Dixie-Lee, Meyerowitz, Elliot M., Bargmann, Cornelia I., Van Der Bliek, Alexander M.

Drosophila shibire and its mammalian homologue dynamin regulate an early step in endocytosis. We identified a Caenorhabditis elegans dynamin gene, dyn-1, based upon hybridization to the Drosophila...

Contribution of the GTPase Domain to the Subcellular Localization of Dynamin in the Nematode Caenorhabditis elegans

Labrousse, Arnaud M., Shurland, Dixie-Lee, Van Der Bliek, Alexander M.

Caenorhabditis elegans dynamin is expressed at high levels in neurons and at lower levels in other cell types, consistent with the important role that dynamin plays in the recycling of synaptic...

Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Smirnova, Elena, Griparic, Lorena, Shurland, Dixie-Lee, Van Der Bliek, Alexander M.

Mutations in the human dynamin-related protein Drp1 cause mitochondria to form perinuclear clusters. We show here that these mitochondrial clusters consist of highly interconnected mitochondrial...

A Human Dynamin-related Protein Controls the Distribution of Mitochondria

Smirnova, Elena, Shurland, Dixie-Lee, Ryazantsev, Sergey N., Van Der Bliek, Alexander M.

Mitochondria exist as a dynamic tubular network with projections that move, break, and reseal in response to local environmental changes. We present evidence that a human dynamin-related protein...