Dirk H. Hellhammer

Influence of prenatal psychosocial stress on cytokine production in adult women (2008)

Entringer, Sonja, Kumsta, Robert, Nelson, Edward L., Hellhammer, Dirk H., Wadhwa, Pathik D., Wüst, Stefan

The aim of the present study was to determine the association between prenatal stress and immune function in human adults. Peripheral blood mononuclear cells (PBMCs) from 34 healthy young women whose...

Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress (2007)

Kumsta, Robert, Entringer, Sonja, Koper, Jan Willem, Hellhammer, Dirk H., Wüst, Stefan

Background: Alterations in glucocorticoid (GC) signaling have been associated with a number of psychiatric disorders. Genetic variation of the glucocorticoid receptor (GR) might be one of the factors...

Cortisol and ACTH responses to psychosocial stress are modulated by corticosteroid binding globulin levels (2007)

Kumsta, Robert, Entringer, Sonja, Hellhammer, Dirk H., Wüst, Stefan

The hypothalamus–pituitary–adrenal (HPA) axis is vital for an organisms’ response to physiological and psychological stress. Cortisol, secreted upon activation of the HPA axis, impacts on...

Cortisol and ACTH responses to psychosocial stress are modulated by corticosteroid binding globulin levels (2007)

Kumsta, Robert, Entringer, Sonja, Hellhammer, Dirk H., Wüst, Stefan

The hypothalamus–pituitary–adrenal (HPA) axis is vital for an organisms’ response to physiological and psychological stress. Cortisol, secreted upon activation of the HPA axis, impacts on...

Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress (2007)

Kumsta, Robert, Entringer, Sonja, Koper, Jan W., Hellhammer, Dirk H., Wüst, Stefan

Background Alterations in glucocorticoid (GC) signaling have been associated with a number of psychiatric disorders. Genetic variation of the glucocorticoid receptor (GR) might be one of the factors...

Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses (2007)

Kumsta, Robert, Entringer, Sonja, Koper, Jan Willem, Van Rossum, Elisabeth, Hellhammer, Dirk H., Wüst, Stefan

Background: Alterations in glucocorticoid (GC) signaling have been associated with a number of psychiatric disorders. Genetic variation of the glucocorticoid receptor (GR) might be one of the factors...

Parity does not alter baseline or stimulated activity of the hypothalamus-pituitary-adrenal axis in women (2006)

Federenko, Ilona S., Wolf, Jutta M., Wust, Stefan, Schlotz, Wolff, Hellhammer, Juliane, Kudielka, Brigitte M., ...

Pregnancy is associated with considerable physiological adaptations, some of which long outlast the state of pregnancy. Although it is well documented that pregnancy produces alterations of the...

The heritability of perceived stress (2006)

Federenko, Ilona S., Schlotz, Wolff, Kirschbaum, Clemens, Bartels, Meike, Hellhammer, Dirk H., Wüst, Stefan

Background. Exploration of the degree to which perceived chronic stress is heritable is important as these self-reports have been linked to stress-related health outcomes. The aims of this study were...

Association of a polymorphism in the H6PD gene and basal cortisol secretion, body fat mass and leptin level (Assoziation eines Polymorphismus im H6PD Gen mit basaler Cortisolsekretion, Fettmasse und Leptinwerten) (2005)

Bellingrath, Silja, Kumsta, Robert, Meyer, Jobst, Moser, Dirk, Federenko, Ilona S., Hellhammer, Dirk H., ...

The hypothalamus-pituitary-adrenal (HPA) axix is vital for an organism's response to physical or psychosocial stimulation. Chronic dysregulation of HPA axis activity is related to several psychiatric...

A psychobiological perspective on genetic determinants of hypothalamus-pituitary-adrenal axis activity (2004)

Wüst, Stefan, Federenko, Ilona S., Koper, Jan Willem, Kumsta, Robert, Entringer, Sonja, ...

From the perspective of psychobiological stress research we present a brief overview of findings documenting a significant impact of genetic factors on the activity of the...

A psychobiological perspective on genetic determinants of hypothalamus-pituitary-adrenal axis activity (2004)

Wüst, Stefan, Federenko, Ilona S., Koper, Jan Willem, Kumsta, Robert, Entringer, Sonja, ...

From the perspective of psychobiological stress research we present a brief overview of findings documenting a significant impact of genetic factors on the activity of the...

Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocrticol responses to psychosocial stress (2004)

Wüst, Stephan, Federenko, Ilona S., Koper, Jan W., Kumsta, Robert, Hellhammer, Dirk H.

Chronic dysregulation of hypothalamus-pituitary-adrenal axis activity is related to several stress-related disorders. Evidence suggests that polymorphisms in the glucocorticoid receptor (GR) gene may...

Free cortisol awakening responses are influenced by awakening time (2004)

Federenko, Ilona, Wüst, Stefan, Hellhammer, Dirk H., Dechoux, Ralph, Kumsta, Robert, Kirschbaum, Clemens

Psychobiological investigations on the hypothalamus–pituitary–adrenal (HPA) axis depend on markers that adequately describe the activity of this system. There is evidence that the free cortisol...

Free cortisol awakening responses are influenced by awakening time (2004)

Federenko, Ilona, Wüst, Stefan, Hellhammer, Dirk H., Dechoux, Ralf, Kumsta, Robert, Kirschbaum, Clemens

Psychobiological investigations on the hypothalamus–pituitary–adrenal (HPA) axis depend on markers that adequately describe the activity of this system. There is evidence that the free cortisol...

Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress (2004)

Wüst, Stefan, Federenko, Ilona S., Koper, Jan Willem, Kumsta, Robert, Hellhammer, Dirk H.

Chronic dysregulation of hypothalamus-pituitary-adrenal axis activity is related to several stress-related disorders. Evidence suggests that polymorphisms in the glucocorticoid receptor (GR) gene may...

Differential Heart Rate Reactivity and Recovery After Psychosocial Stress (TSST) in Healthy Children, Younger Adults, and Elderly Adults: The Impact of Age and Gender (2004)

Kudielka, Brigitte M., Buske-Kirschbaum, Angelika, Hellhammer, Dirk H., Kirschbaum, Clemens

In addition to numerous reports about psychophysiological stress responses to acute stressors, there are few data available on gender differences of stress-induced heart rate responses in multiple...