Dimitri Niks

Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex (2007)

Ngo, Huu, Harris, Rodney, Kimmich, Novelle, Casino, Patricia, Niks, Dimitri, Blumenstein, Lars, ...

βQ114N and βT110V Mutations Reveal a Critically Important Role of the Substrate α-Carboxylate Site in the Reaction Specificity of Tryptophan Synthase (2007)

Blumenstein, Lars, Domratcheva, Tatiana, Niks, Dimitri, Ngo, Huu, Seidel, Ralf, Dunn, Michael F, ...

βQ114M and βT110V Mutations Reveal a Critically Important Role of the Substrate Α−Carboxylate Site in the Reaction Specificity of Tryptophan Synthase (2007)

Blumenstein, Lars, Domratcheva, Tatiana, Niks, Dimitri, Ngo, Huu, Seidel, Ralf, Dunn, Michael F., ...

In the PLP−requiring α2α2 tryptophan synthase complex, recognition of the substrate L−Ser at the β−site includes a loop structure (residues β110−115) extensively H−bonded to the...

Synthesis and Characterization of Allosteric Probes of Substrate Channeling in the Tryptophan Synthase Bienzyme Complex (2007)

Ngo, Huu, Harris, Rodney, Kimmich, Novelle, Casino, Patricia, Niks, Dimitri, Blumenstein, Lars, ...

Allosteric interactions regulate substrate channeling in Salmonella typhimurium tryptophan synthase. The channeling of indole between the Alpha− and ß−sites via the interconnecting 25 Å...

On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella typhimurium and BX1 from Maize, Two Evolutionarily Related Enzymes (2005)

Kulik,Victor, Hartmann,Elisabeth, Weyand,Michael, Frey,Monika, Gierl,Alfons, Niks,Dimitri, ...

On the Structural Basis of the Catalytic Mechanism and the Regulation of the Alpha Subunit of Tryptophan Synthase from Salmonella typhimurium and BX1 from Maize, Two Evolutionarily Related Enzymes (2005)

Kulik, Victor, Hartmann, Elisabeth, Weyand, Michael, Frey, Monika, Gierl, Alfons, Niks, Dimitri, ...

On the Role of αThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase (2002)

Kulik,Victor, Weyand,Michael, Seidel,Ralf, Niks,Dimitri, Arac,Demet, Dunn,Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5-phosphate-dependent tryptophan synthase α 2β 2 complex is regulated by allosteric interactions that modulate the switching of the...

On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase (2002)

Kulik,Victor, Weyand,Michael, Seidel,Ralf, Niks,Dimitri, Arac,Demet, Dunn,Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5'-phosphate-dependent tryptophan synthase alpha(2)beta(2) complex is regulated by allosteric interactions that modulate the switching...

On the role of αThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase (2002)

Kulik, Victor, Weyand, Michael, Seidel, Ralf, Niks, Dimitri, Arac, Demet, Dunn, Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5'-phosphate-dependent tryptophan synthase alpha(2)beta(2) complex is regulated by allosteric interactions that modulate the switching...

On the Role of αThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase (2002)

Kulik, Victor, Weyand, Michael, Seidel, Ralf, Niks, Dimitri, Arac, Demet, Dunn, Michael F., ...

The catalytic activity and substrate channeling of the pyridoxal 5-phosphate-dependent tryptophan synthase α 2β 2 complex is regulated by allosteric interactions that modulate the switching of the...