Notch/Delta signaling constrains reengineering of pro-T cells by PU.1 (2006)
Franco, Christopher B., Scripture-Adams, Dierdre D., Proekt, Irina, Taghon, Tom, Weiss, Angela H., Yui, Mary A., ...
PU.1 is essential for early stages of mouse T cell development but antagonizes it if expressed constitutively. Two separable mechanisms are involved: attenuation and diversion. Dysregulated PU.1...
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry (2006)
Groszer, Matthias, Erickson, Rebecca, Scripture-Adams, Dierdre D., Dougherty, Jospeh D., Le Belle, Janel, Zack, Jerome A., ...
Previous studies have demonstrated that a small subpopulation of brain tumor cells share key characteristics with neural stem/progenitor cells in terms of phenotype and behavior. These findings...