Dennis Merkle

DNA double strand break repair : a biophysical study (2004)

Merkle, Dennis

Bibliography : p. 122-139. Some pages are in colour.

DNA double strand break repair : a biophysical study (2004)

Merkle, Dennis

Bibliography : p. 122-139. Some pages are in colour.

Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine

Block, Wesley D., Merkle, Dennis, Meek, Katheryn, Lees-Miller, Susan P.

Caffeine inhibits cell cycle checkpoints, sensitizes cells to ionizing radiation-induced cell killing and inhibits the protein kinase activity of two cell cycle checkpoint regulators,...

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends

Block, Wesley D., Yu, Yaping, Merkle, Dennis, Gifford, Jessica L., Ding, Qi, Meek, Katheryn, ...

Non-homologous end joining (NHEJ) is one of the primary pathways for the repair of ionizing radiation (IR)-induced DNA double-strand breaks (DSBs) in mammalian cells. Proteins required for NHEJ...

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

Douglas, Pauline, Sapkota, Gopal P, Morrice, Nick, Yu, Yaping, Goodarzi, Aaron A, Merkle, Dennis, ...

The DNA-dependent protein kinase (DNA-PK) is required for the repair of DNA double-strand breaks (DSBs), such as those caused by ionizing radiation and other DNA-damaging agents. DNA-PK is composed...

In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5

Ohrt, Thomas, Merkle, Dennis, Birkenfeld, Karin, Echeverri, Christophe J., Schwille, Petra

Two types of short double-stranded RNA molecules, namely microRNAs (miRNAs) and short interfering RNAs (siRNAs), have emerged recently as important regulators of gene expression. Although these...

Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine

Block, Wesley D., Merkle, Dennis, Meek, Katheryn, Lees-Miller, Susan P.

Caffeine inhibits cell cycle checkpoints, sensitizes cells to ionizing radiation-induced cell killing and inhibits the protein kinase activity of two cell cycle checkpoint regulators,...

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends

Block, Wesley D., Yu, Yaping, Merkle, Dennis, Gifford, Jessica L., Ding, Qi, Meek, Katheryn, ...

Non-homologous end joining (NHEJ) is one of the primary pathways for the repair of ionizing radiation (IR)-induced DNA double-strand breaks (DSBs) in mammalian cells. Proteins required for NHEJ...

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.

Douglas, Pauline, Sapkota, Gopal P, Morrice, Nick, Yu, Yaping, Goodarzi, Aaron A, Merkle, Dennis, ...

The DNA-dependent protein kinase (DNA-PK) is required for the repair of DNA double-strand breaks (DSBs), such as those caused by ionizing radiation and other DNA-damaging agents. DNA-PK is composed...

In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5

Ohrt, Thomas, Merkle, Dennis, Birkenfeld, Karin, Echeverri, Christophe J., Schwille, Petra

Two types of short double-stranded RNA molecules, namely microRNAs (miRNAs) and short interfering RNAs (siRNAs), have emerged recently as important regulators of gene expression. Although these...