Genome-wide association study identifies novel breast cancer susceptibility loci (2007)
Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D.P., Thompson, Deborah, Ballinger, Dennis G., ...
Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast...
Genome-wide association study identifies novel breast cancer susceptibility loci (2007)
Easton, Douglas F., Pooley, Karen A., Dunning, Alison M., Pharoah, Paul D. P., Thompson, Deborah, Ballinger, Dennis G., ...
Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast...
Fine-scale recombination patterns differ between chimpanzees and humans (2005)
Ptak, Susan E., Hinds, David A., Koehler, Kathrin, Nickel, Birgit, Patil, Nila, Ballinger, Dennis G., ...
Inversions, deletions and insertions are important mediators of disease and disease susceptibility. We systematically compared the human genome reference sequence with a second genome (represented by...
High-Resolution Whole-Genome Association Study of Parkinson Disease
Maraganore, Demetrius M., De Andrade, Mariza, Lesnick, Timothy G., Strain, Kari J., Farrer, Matthew J., Rocca, Walter A., ...
We performed a two-tiered, whole-genome association study of Parkinson disease (PD). For tier 1, we individually genotyped 198,345 uniformly spaced and informative single-nucleotide polymorphisms...
Analysis of allelic differential expression in human white blood cells
Pant, P.V. Krishna, Tao, Heng, Beilharz, Erica J., Ballinger, Dennis G., Cox, David R., Frazer, Kelly A.
Allelic variation of gene expression is common in humans, and is of interest because of its potential contribution to variation in heritable traits. To identify human genes with allelic expression...
Response from Maraganore et al.
Maraganore, Demetrius M., Andrade, Mariza De, Lesnick, Timothy G., Pant, P. V. Krishna, Cox, David R., Ballinger, Dennis G.
Matching Strategies for Genetic Association Studies in Structured Populations
Hinds, David A., Stokowski, Renee P., Patil, Nila, Konvicka, Karel, Kershenobich, David, Cox, David R., ...
Association studies in populations that are genetically heterogeneous can yield large numbers of spurious associations if population subgroups are unequally represented among cases and controls. This...
High-Resolution Whole-Genome Association Study of Parkinson Disease
Maraganore, Demetrius M., De Andrade, Mariza, Lesnick, Timothy G., Strain, Kari J., Farrer, Matthew J., Rocca, Walter A., ...
We performed a two-tiered, whole-genome association study of Parkinson disease (PD). For tier 1, we individually genotyped 198,345 uniformly spaced and informative single-nucleotide polymorphisms...
Analysis of allelic differential expression in human white blood cells
Pant, P.V. Krishna, Tao, Heng, Beilharz, Erica J., Ballinger, Dennis G., Cox, David R., Frazer, Kelly A.
Allelic variation of gene expression is common in humans, and is of interest because of its potential contribution to variation in heritable traits. To identify human genes with allelic expression...
Response from Maraganore et al.
Maraganore, Demetrius M., Andrade, Mariza De, Lesnick, Timothy G., Pant, P. V. Krishna, Cox, David R., Ballinger, Dennis G.
Tian, Chao, Hinds, David A., Shigeta, Russell, Kittles, Rick, Ballinger, Dennis G., Seldin, Michael F.
Admixture mapping requires a genomewide panel of relatively evenly spaced markers that can distinguish the ancestral origins of chromosomal segments in admixed individuals. Through use of the results...