Deirdre D. Scripture-Adams

Interleukin-7 Induces Expression of Latent Human Immunodeficiency Virus Type 1 with Minimal Effects on T-Cell Phenotype

Scripture-Adams, Deirdre D., Brooks, David G., Korin, Yael D., Zack, Jerome A.

Latent human immunodeficiency virus type 1 (HIV-1) persists even in patients treated with antiretroviral therapy. New treatment strategies are therefore needed to eradicate this latent viral...

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

Groszer, Matthias, Erickson, Rebecca, Scripture-Adams, Deirdre D., Dougherty, Joseph D., Le Belle, Janel, Zack, Jerome A., ...

Previous studies have demonstrated that a small subpopulation of brain tumor cells share key characteristics with neural stem/progenitor cells in terms of phenotype and behavior. These findings...

Interleukin-7 Induces Expression of Latent Human Immunodeficiency Virus Type 1 with Minimal Effects on T-Cell Phenotype

Scripture-Adams, Deirdre D., Brooks, David G., Korin, Yael D., Zack, Jerome A.

Latent human immunodeficiency virus type 1 (HIV-1) persists even in patients treated with antiretroviral therapy. New treatment strategies are therefore needed to eradicate this latent viral...

PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry

Groszer, Matthias, Erickson, Rebecca, Scripture-Adams, Deirdre D., Dougherty, Joseph D., Le Belle, Janel, Zack, Jerome A., ...

Previous studies have demonstrated that a small subpopulation of brain tumor cells share key characteristics with neural stem/progenitor cells in terms of phenotype and behavior. These findings...

Notch/Delta signaling constrains reengineering of pro-T cells by PU.1

Franco, Christopher B., Scripture-Adams, Deirdre D., Proekt, Irina, Taghon, Tom, Weiss, Angela H., Yui, Mary A., ...

PU.1 is essential for early stages of mouse T cell development but antagonizes it if expressed constitutively. Two separable mechanisms are involved: attenuation and diversion. Dysregulated PU.1...