De Witt Sumners

Cerebellar Isolation, Parcellation, and Conformal Mapping (2001)

Kelly Rehm, Monica Hurdal, Josh Stern, Kirt Schaper, De Witt Sumners

Why map the cerebellar surface? Because: (i) organization of motor, sensory and cognitive functions in the human cerebellum is poorly understood [1], (ii) the highly-folded structure conceals most of...

Novel display of knotted DNA molecules by two-dimensional gel electrophoresis

Trigueros, Sonia, Arsuaga, Javier, Vazquez, Maria E., Sumners, De Witt, Roca, Joaquim

We describe a two-dimensional agarose gel electrophoresis procedure that improves the resolution of knotted DNA molecules. The first gel dimension is run at low voltage, and DNA knots migrate...

Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids

Arsuaga, Javier, Vázquez, Mariel, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim

When linear double-stranded DNA is packed inside bacteriophage capsids, it becomes highly compacted. However, the phage is believed to be fully effective only if the DNA is not entangled....

DNA knots reveal a chiral organization of DNA in phage capsids

Arsuaga, Javier, Vazquez, Mariel, McGuirk, Paul, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim

Icosahedral bacteriophages pack their double-stranded DNA genomes to near-crystalline density and achieve one of the highest levels of DNA condensation found in nature. Despite numerous studies, some...

Novel display of knotted DNA molecules by two-dimensional gel electrophoresis

Trigueros, Sonia, Arsuaga, Javier, Vazquez, Maria E., Sumners, De Witt, Roca, Joaquim

We describe a two-dimensional agarose gel electrophoresis procedure that improves the resolution of knotted DNA molecules. The first gel dimension is run at low voltage, and DNA knots migrate...

Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids

Arsuaga, Javier, Vázquez, Mariel, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim

When linear double-stranded DNA is packed inside bacteriophage capsids, it becomes highly compacted. However, the phage is believed to be fully effective only if the DNA is not entangled....

DNA knots reveal a chiral organization of DNA in phage capsids

Arsuaga, Javier, Vazquez, Mariel, McGuirk, Paul, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim

Icosahedral bacteriophages pack their double-stranded DNA genomes to near-crystalline density and achieve one of the highest levels of DNA condensation found in nature. Despite numerous studies, some...