David Tarlinton

The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells (2002)

Pohl, Thomas, Gugasyan, Raffi, Grumont, Raelene J., Strasser, Andreas, Metcalf, Donald, Tarlinton, David, ...

Transcription factors NF-KB1 and c-Rel, individually dispensable during embryogenesis, serve similar, yet distinct, roles in the function of mature hemopoietic cells. Redundancy among Rel/ NF-KB...

The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

Pohl, Thomas, Gugasyan, Raffi, Grumont, Raelene J., Strasser, Andreas, Metcalf, Donald, Tarlinton, David, ...

Transcription factors NF-κB1 and c-Rel, individually dispensable during embryogenesis, serve similar, yet distinct, roles in the function of mature hemopoietic cells. Redundancy among Rel/NF-κB...

The Absence of Tssc6, a Member of the Tetraspanin Superfamily, Does Not Affect Lymphoid Development but Enhances In Vitro T-Cell Proliferative Responses

Tarrant, Jacqueline M., Groom, Joanna, Metcalf, Donald, Li, Ruili, Borobokas, Bette, Wright, Mark D., ...

The tetraspanins are a family of integral membrane proteins with four transmembrane domains. These molecules form multimolecular networks on the surfaces of many different cell types. Gene-targeting...

SOCS5 Is Expressed in Primary B and T Lymphoid Cells but Is Dispensable for Lymphocyte Production and Function

Brender, Christine, Columbus, Ruth, Metcalf, Donald, Handman, Emanuela, Starr, Robyn, Huntington, Nick, ...

Suppressors of cytokine signaling (SOCSs) are key regulators of cytokine-induced responses in hematopoietic as well as nonhematopoietic cells. SOCS1 and SOCS3 have been shown to modulate T-cell...

The combined absence of NF-κB1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

Pohl, Thomas, Gugasyan, Raffi, Grumont, Raelene J., Strasser, Andreas, Metcalf, Donald, Tarlinton, David, ...

Transcription factors NF-κB1 and c-Rel, individually dispensable during embryogenesis, serve similar, yet distinct, roles in the function of mature hemopoietic cells. Redundancy among Rel/NF-κB...

The Absence of Tssc6, a Member of the Tetraspanin Superfamily, Does Not Affect Lymphoid Development but Enhances In Vitro T-Cell Proliferative Responses

Tarrant, Jacqueline M., Groom, Joanna, Metcalf, Donald, Li, Ruili, Borobokas, Bette, Wright, Mark D., ...

The tetraspanins are a family of integral membrane proteins with four transmembrane domains. These molecules form multimolecular networks on the surfaces of many different cell types. Gene-targeting...

SOCS5 Is Expressed in Primary B and T Lymphoid Cells but Is Dispensable for Lymphocyte Production and Function

Brender, Christine, Columbus, Ruth, Metcalf, Donald, Handman, Emanuela, Starr, Robyn, Huntington, Nick, ...

Suppressors of cytokine signaling (SOCSs) are key regulators of cytokine-induced responses in hematopoietic as well as nonhematopoietic cells. SOCS1 and SOCS3 have been shown to modulate T-cell...

bcl-2 Transgene Expression Inhibits Apoptosis in the Germinal Center and Reveals Differences in the Selection of Memory B Cells and Bone Marrow Antibody-Forming Cells

Smith, Kenneth G.C., Light, Amanda, O'Reilly, Lorraine A., Ang, Soon-Meng, Strasser, Andreas, Tarlinton, David

Immunization with T cell–dependent antigens generates long-lived memory B cells and antibody-forming cells (AFCs). Both populations originate in germinal centers and, predominantly, produce...