David S. Shames

sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database (2007)

Shah, Jyoti K, Garner, Harold R, White, Michael A, Shames, David S, Minna, John D

Abstract Background RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdown of gene...

A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies (2006)

David S. Shames, Luc Girard, Boning Gao, Mitsuo Sato, Cheryl M. Lewis, Narayan Shivapurkar, ...

BackgroundPromoter hypermethylation coupled with loss of heterozygosity at the same locus results in loss of gene function in many tumor cells. The “rules” governing which genes are methylated...

A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies

Shames, David S, Girard, Luc, Gao, Boning, Sato, Mitsuo, Lewis, Cheryl M, Shivapurkar, Narayan, ...

John Minna and colleagues report that a group of genes are commonly methylated in primary lung, breast, colon, and prostate cancer.

sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database

Shah, Jyoti K, Garner, Harold R, White, Michael A, Shames, David S, Minna, John D

IP6K2 is a client for HSP90 and a target for cancer therapeutics development

Shames, David S., Minna, John D.