Olivieri, Kevin C, Scoggins, Robert M, Broderick, Brooks, Powell, Maria LC, Alexander, Melissa A, Hammarskjöld, Marie-Louise, ...
Abstract AIDS-associated, CCR5-tropic (R5) HIV-1 clones, isolated from a patient that never developed CXCR4-tropic HIV-1, replicate to a greater extent and cause greater cytopathic effects than R5...
DBR1 siRNA inhibition of HIV-1 replication (2005)
Ye, Ying, De Leon, Jessica, Yokoyama, Noriko, Naidu, Yathi, Camerini, David
Abstract Background HIV-1 and all retroviruses are related to retroelements of simpler organisms such as the yeast Ty elements. Recent work has suggested that the yeast retroelement Ty1 replicates...
DBR1 siRNA inhibition of HIV-1 replication. (2005)
Ye, Ying, De Leon, Jessica, Yokoyama, Noriko, Naidu, Yathi, Camerini, David
Background: HIV-1 and all retroviruses are related to retroelements of simpler organisms such as the yeast Ty elements. Recent work has suggested that the yeast retroelement Ty1 replicates via an...
Camerini, David, Su, Hua-Poo, Gamez-Torre, Graciela, Johnson, Michael L., Zack, Jerome A., Chen, Irvin S. Y.
Human immunodeficiency virus type 1 (HIV-1) patient isolates and molecular clones were used to analyze the determinants responsible for human CD4+ thymocyte depletion in SCID-hu mice....
Pathogenesis of Primary R5 Human Immunodeficiency Virus Type 1 Clones in SCID-hu Mice
Scoggins, Robert M., Taylor, James R., Patrie, James, Van't Wout, Angélique B., Schuitemaker, Hanneke, Camerini, David
We studied the replication and cytopathicity in SCID-hu mice of R5 human immunodeficiency virus type 1 (HIV-1) biological clones from early and late stages of infection of three patients who never...
Taylor, James R., Kimbrell, Katherine C., Scoggins, Robert, Delaney, Marie, Wu, Lijun, Camerini, David
The presence or absence of the receptor CD4 and the coreceptors CCR5 and CXCR4 restrict the cell tropism of human immunodeficiency virus type 1 (HIV-1). Despite the importance of thymic infection by...
Zimmerman, Erik S., Chen, Junjie, Andersen, Joshua L., Ardon, Orly, DeHart, Jason L., Blackett, Jana, ...
Eukaryotic cells have evolved a complex mechanism for sensing DNA damage during genome replication. Activation of this pathway prevents entry into mitosis to allow for either DNA repair or, in the...
Choudhary, Shailesh K., Choudhary, Neelima R., Kimbrell, Katherine C., Colasanti, Jonathan, Ziogas, Argyrios, Kwa, David, ...
Late-stage CCR5 tropic human immunodeficiency virus type 1 (HIV-1) isolates (R5 HIV-1) can deplete nearly all CD4+ thymocytes from human thymus/liver grafts, despite the fact that fewer than 5% of...
DBR1 siRNA inhibition of HIV-1 replication
Ye, Ying, De Leon, Jessica, Yokoyama, Noriko, Naidu, Yathi, Camerini, David
KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice
Parsons, Christopher H., Adang, Laura A., Overdevest, Jon, O’Connor, Christine M., Taylor, J. Robert, Camerini, David, ...
To develop an animal model of Kaposi sarcoma–associated herpesvirus (KSHV) infection uniquely suited to evaluate longitudinal patterns of viral gene expression, cell tropism, and immune responses,...
Camerini, David, Su, Hua-Poo, Gamez-Torre, Graciela, Johnson, Michael L., Zack, Jerome A., Chen, Irvin S. Y.
Human immunodeficiency virus type 1 (HIV-1) patient isolates and molecular clones were used to analyze the determinants responsible for human CD4+ thymocyte depletion in SCID-hu mice....
Pathogenesis of Primary R5 Human Immunodeficiency Virus Type 1 Clones in SCID-hu Mice
Scoggins, Robert M., Taylor, James R., Patrie, James, Van't Wout, Angélique B., Schuitemaker, Hanneke, Camerini, David
We studied the replication and cytopathicity in SCID-hu mice of R5 human immunodeficiency virus type 1 (HIV-1) biological clones from early and late stages of infection of three patients who never...
Taylor, James R., Kimbrell, Katherine C., Scoggins, Robert, Delaney, Marie, Wu, Lijun, Camerini, David
The presence or absence of the receptor CD4 and the coreceptors CCR5 and CXCR4 restrict the cell tropism of human immunodeficiency virus type 1 (HIV-1). Despite the importance of thymic infection by...
Zimmerman, Erik S., Chen, Junjie, Andersen, Joshua L., Ardon, Orly, DeHart, Jason L., Blackett, Jana, ...
Eukaryotic cells have evolved a complex mechanism for sensing DNA damage during genome replication. Activation of this pathway prevents entry into mitosis to allow for either DNA repair or, in the...
Choudhary, Shailesh K., Choudhary, Neelima R., Kimbrell, Katherine C., Colasanti, Jonathan, Ziogas, Argyrios, Kwa, David, ...
Late-stage CCR5 tropic human immunodeficiency virus type 1 (HIV-1) isolates (R5 HIV-1) can deplete nearly all CD4+ thymocytes from human thymus/liver grafts, despite the fact that fewer than 5% of...
DBR1 siRNA inhibition of HIV-1 replication
Ye, Ying, De Leon, Jessica, Yokoyama, Noriko, Naidu, Yathi, Camerini, David
KSHV targets multiple leukocyte lineages during long-term productive infection in NOD/SCID mice
Parsons, Christopher H., Adang, Laura A., Overdevest, Jon, O’Connor, Christine M., Taylor, J. Robert, Camerini, David, ...
To develop an animal model of Kaposi sarcoma–associated herpesvirus (KSHV) infection uniquely suited to evaluate longitudinal patterns of viral gene expression, cell tropism, and immune responses,...
Choudhary, Shailesh K., Vrisekoop, Nienke, Jansen, Christine A., Otto, Sigrid A., Schuitemaker, Hanneke, Miedema, Frank, ...
Long-term asymptomatic human immunodeficiency virus (HIV)-infected individuals (LTA) usually have low viral load and low immune activation. To discern whether viral load or immune activation is...
Olivieri, Kevin C, Scoggins, Robert M, Broderick, Brooks, Powell, Maria LC, Alexander, Melissa A, Hammarskjöld, Marie-Louise, ...
AIDS-associated, CCR5-tropic (R5) HIV-1 clones, isolated from a patient that never developed CXCR4-tropic HIV-1, replicate to a greater extent and cause greater cytopathic effects than R5 HIV-1...