Danni Ramduth

Immune Selection for Altered Antigen Processing Leads to Cytotoxic T Lymphocyte Escape in Chronic HIV-1 Infection

Draenert, Rika, Le Gall, Sylvie, Pfafferott, Katja J., Leslie, Alasdair J., Chetty, Polan, Brander, Christian, ...

Mutations within cytotoxic T lymphocyte (CTL) epitopes impair T cell recognition, but escape mutations arising in flanking regions that alter antigen processing have not been defined in natural human...

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA

Leslie, Alasdair, Kavanagh, Daniel, Honeyborne, Isobella, Pfafferott, Katja, Edwards, Charles, Pillay, Tilly, ...

Human immunodeficiency virus (HIV)-1 amino acid sequence polymorphisms associated with expression of specific human histocompatibility leukocyte antigen (HLA) class I alleles suggest sites of...