Daniel R. Rines

Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells (2008)

Rines, Daniel R, Gomez-Ferreria, Maria, Zhou, Yingyao, DeJesus, Paul, Grob, Seanna, Batalov, Serge, ...

Abstract Background The mitotic spindle is a complex mechanical apparatus required for accurate segregation of sister chromosomes during mitosis. We designed a genetic screen using automated...

A role for IκB kinase 2 in bipolar spindle assembly

Irelan, Jeffrey T., Murphy, Thomas J., DeJesus, Paul D., Teo, Hsiangling, Xu, DingYue, Gomez-Ferreria, Maria A., ...

IκB kinase 2 (IKK2 or IKKβ) is a component of the IKK complex that coordinates the cellular response to a diverse set of extracellular stimuli, including cytokines, microbial infection, and stress....

Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells

Rines, Daniel R, Gomez-Ferreria, Maria Ana, Zhou, Yingyao, DeJesus, Paul, Grob, Seanna, Batalov, Serge, ...

A loss-of-function screen for siRNAs that arrest human cells in metaphase reveals genes involved in mitotic spindle integrity.