Daniel G. Rosen

Correlation between CpG methylation profiles and hormone receptor status in breast cancers (2007)

Feng, Weiwei, Shen, Lanlan, Wen, Sijin, Rosen, Daniel G, Jelinek, Jaroslav, Hu, Xin, ...

Abstract Introduction Aberrant DNA methylation has been found frequently in human breast cancers, associated with the loss of expression of a number of regulatory genes for growth and correlated to...

WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome (2005)

Nunez, María I, Rosen, Daniel G, Ludes-Meyers, John H, Abba, Martín C, Kil, Hyunsuk, Page, Robert, ...

Abstract Background The putative tumor suppressor WWOX gene spans the common chromosomal fragile site 16D (FRA16D) at chromosome area 16q23.3-24.1. This region is a frequent target for loss of...

Atypical PKCι contributes to poor prognosis through loss of apical-basal polarity and Cyclin E overexpression in ovarian cancer

Eder, Astrid M., Sui, Xiaomei, Rosen, Daniel G., Nolden, Laura K, Cheng, Kwai Wa, Lahad, John P., ...

We show that atypical PKCι, which plays a critical role in the establishment and maintenance of epithelial cell polarity, is genomically amplified and overexpressed in serous epithelial ovarian...

Atypical PKCι contributes to poor prognosis through loss of apical-basal polarity and Cyclin E overexpression in ovarian cancer

Eder, Astrid M., Sui, Xiaomei, Rosen, Daniel G., Nolden, Laura K, Cheng, Kwai Wa, Lahad, John P., ...

We show that atypical PKCι, which plays a critical role in the establishment and maintenance of epithelial cell polarity, is genomically amplified and overexpressed in serous epithelial ovarian...

The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

Yang, Gong, Rosen, Daniel G., Zhang, Zhihong, Bast, Robert C., Mills, Gordon B., Colacino, Justin A., ...

Epithelial–stromal interactions play a critical role in tumor initiation and progression; cancer-associated stroma, but not normal stroma, is known to be tumor-promoting. However, the molecular...