Aging Impacts Transcriptome but not Genome of Hormone-dependent Breast Cancers (2007)
Yau, Christina, Fedele, Vita, Roydasgupta, Ritu, Fridlyand, Jane, Hubbard, Alan, Gray, Joe W., ...
Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers (2007)
Yau, Christina, Fedele, Vita, Roydasgupta, Ritu, Fridlyand, Jane, Hubbard, Alan, Gray, Joe W, ...
Abstract Introduction Age is one of the most important risk factors for human malignancies, including breast cancer; in addition, age at diagnosis has been shown to be an independent indicator of...
Korkola, James E, Blaveri, Ekaterina, DeVries, Sandy, Moore, Dan H, Hwang, E Shelley, Chen, Yunn-Yi, ...
Abstract Background Breast cancer is a heterogeneous disease, presenting with a wide range of histologic, clinical, and genetic features. Microarray technology has shown promise in predicting outcome...
Zhou, Yamei, Yau, Christina, Gray, Joe W, Chew, Karen, Dairkee, Shanaz H, Moore, Dan H, ...
Abstract Background Signaling pathways that converge on two different transcription factor complexes, NFκB and AP-1, have been identified in estrogen receptor (ER)-positive breast cancers resistant...
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H., Kerlikowske, Karla
Providing information about the risk of disease and clinical factors that may increase or decrease a patient's risk of disease is standard medical practice. Although case-control studies can provide...
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H., Kerlikowske, Karla
Providing information about the risk of disease and clinical factors that may increase or decrease a patient's risk of disease is standard medical practice. Although case-control studies can provide...
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H., Kerlikowske, Karla
Providing information about the risk of disease and clinical factors that may increase or decrease a patient's risk of disease is standard medical practice. Although case-control studies can provide...
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H., Kerlikowske, Karla
Providing information about the risk of disease and clinical factors that may increase or decrease a patient's risk of disease is standard medical practice. Although case-control studies can provide...
A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue (2004)
Dairkee, Shanaz H, Ji, Youngran, Ben, Yong, Moore, Dan H, Meng, Zhenhang, Jeffrey, Stefanie S
Abstract Background To identify the spectrum of malignant attributes maintained outside the host environment, we have compared global gene expression in primary breast tumors and matched short-term...
Comparative Genomic Hybridization Array Analysis (2002)
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H.
At the present time, there is increasing evidence that cancer may be regulated by the number of copies of genes in tumor cells. Through microarray technology it is now possible to measure the number...
Comparative Genomic Hybridization Array Analysis (2002)
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H.
At the present time, there is increasing evidence that cancer may be regulated by the number of copies of genes in tumor cells. Through microarray technology it is now possible to measure the number...
Comparative Genomic Hybridization Array Analysis (2002)
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H.
At the present time, there is increasing evidence that cancer may be regulated by the number of copies of genes in tumor cells. Through microarray technology it is now possible to measure the number...
Comparative Genomic Hybridization Array Analysis (2002)
Molinaro, Annette M., Van Der Laan, Mark J., Moore, Dan H.
At the present time, there is increasing evidence that cancer may be regulated by the number of copies of genes in tumor cells. Through microarray technology it is now possible to measure the number...
Separation of B and C Type Virions by Centrifugation in Gentle Density Gradients
Sarkar, Nurul H., Moore, Dan H.
Murine type B particles were separated from type C (Rauscher leukemia virus) by means of gentle (low-increment rate) density gradients. The best separation was obtained when the density ranged from...
Isolation and Characterization of RNA-Directed DNA Polymerase from a B-Type RNA Tumor Virus
Dion, Arnold S., Vaidya, Akhil B., Fout, Garland S., Moore, Dan H.
RNA-directed DNA polymerase was isolated from milk-borne B-type murine mammary tumor virus of the RIII mouse strain. The several hundred-fold-purified enzyme sediments at 5.5 to 5.7S with an average...
Electron Microscopy of the Nucleic Acid of Mouse Mammary Tumor Virus
Sarkar, Nurul H., Moore, Dan H.
Mouse mammary tumor virus (MTV) was isolated from the milk of RIII mice by density-gradient centrifugation in Ficoll. The homogeneity of the preparation was demonstrated in electron micrographs. The...
Helical Nucleocapsid Structure of the Oncogenic Ribonucleic Acid Viruses (Oncornaviruses)
Sarkar, Nurul H., Nowinski, Robert C., Moore, Dan H.
Negative staining of virions and isolated nucleoids from avian myeloblastosis virus, murine leukemia virus, murine mammary tumor virus, and feline leukemia virus reveals common internal structures....
Kramarsky, Bernhard, Sarkar, Nurul H., Moore, Dan H.
The ultrastructure and morphogenesis of Mason-Pfizer monkey virus, isolated from a mammary carcinoma in a Rhesus monkey, was compared with those of murine mammary tumor virus, murine leukemia virus,...
FRACTIONATION OF SERUM PROTEINS IN HYPERPROTEINEMIA, WITH SPECIAL REFERENCE TO MULTIPLE MYELOMA
Gutman, Alexander B., Moore, Dan H., Gutman, Ethel Benedict, McClellan, Virginia, Kabat, Elvin A.
THE RELATION OF CEPHALIN FLOCCULATION AND COLLOIDAL GOLD REACTIONS TO THE SERUM PROTEINS 1
Kabat, Elvin A., Hanger, Franklin M., Moore, Dan H., Landow, Harold
MECHANISM OF THE POSITIVE CEPHALIN-CHOLESTEROL FLOCCULATION REACTION IN HEPATITIS
Moore, David B., Pierson, Paul S., Hanger, Franklin M., Moore, Dan H.
SIGNIFICANCE OF CEPHALIN-CHOLESTEROL FLOCCULATION TEST IN MALARIAL FEVER 1
Guttman, Samuel A., Potter, Harry R., Hanger, Franklin M., Moore, David B., Pierson, Paul S., Moore, Dan H.
A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue
Dairkee, Shanaz H, Ji, Youngran, Ben, Yong, Moore, Dan H, Meng, Zhenhang, Jeffrey, Stefanie S
Separation of B and C Type Virions by Centrifugation in Gentle Density Gradients
Sarkar, Nurul H., Moore, Dan H.
Murine type B particles were separated from type C (Rauscher leukemia virus) by means of gentle (low-increment rate) density gradients. The best separation was obtained when the density ranged from...
Isolation and Characterization of RNA-Directed DNA Polymerase from a B-Type RNA Tumor Virus
Dion, Arnold S., Vaidya, Akhil B., Fout, Garland S., Moore, Dan H.
RNA-directed DNA polymerase was isolated from milk-borne B-type murine mammary tumor virus of the RIII mouse strain. The several hundred-fold-purified enzyme sediments at 5.5 to 5.7S with an average...
Electron Microscopy of the Nucleic Acid of Mouse Mammary Tumor Virus
Sarkar, Nurul H., Moore, Dan H.
Mouse mammary tumor virus (MTV) was isolated from the milk of RIII mice by density-gradient centrifugation in Ficoll. The homogeneity of the preparation was demonstrated in electron micrographs. The...
Helical Nucleocapsid Structure of the Oncogenic Ribonucleic Acid Viruses (Oncornaviruses)
Sarkar, Nurul H., Nowinski, Robert C., Moore, Dan H.
Negative staining of virions and isolated nucleoids from avian myeloblastosis virus, murine leukemia virus, murine mammary tumor virus, and feline leukemia virus reveals common internal structures....
Kramarsky, Bernhard, Sarkar, Nurul H., Moore, Dan H.
The ultrastructure and morphogenesis of Mason-Pfizer monkey virus, isolated from a mammary carcinoma in a Rhesus monkey, was compared with those of murine mammary tumor virus, murine leukemia virus,...
FRACTIONATION OF SERUM PROTEINS IN HYPERPROTEINEMIA, WITH SPECIAL REFERENCE TO MULTIPLE MYELOMA
Gutman, Alexander B., Moore, Dan H., Gutman, Ethel Benedict, McClellan, Virginia, Kabat, Elvin A.
THE RELATION OF CEPHALIN FLOCCULATION AND COLLOIDAL GOLD REACTIONS TO THE SERUM PROTEINS 1
Kabat, Elvin A., Hanger, Franklin M., Moore, Dan H., Landow, Harold
MECHANISM OF THE POSITIVE CEPHALIN-CHOLESTEROL FLOCCULATION REACTION IN HEPATITIS
Moore, David B., Pierson, Paul S., Hanger, Franklin M., Moore, Dan H.
SIGNIFICANCE OF CEPHALIN-CHOLESTEROL FLOCCULATION TEST IN MALARIAL FEVER 1
Guttman, Samuel A., Potter, Harry R., Hanger, Franklin M., Moore, David B., Pierson, Paul S., Moore, Dan H.
A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue
Dairkee, Shanaz H, Ji, Youngran, Ben, Yong, Moore, Dan H, Meng, Zhenhang, Jeffrey, Stefanie S
Genes and pathways downstream of telomerase in melanoma metastasis
Bagheri, Sepideh, Nosrati, Mehdi, Li, Shang, Fong, Sylvia, Torabian, Sima, Rangel, Javier, ...
Recent studies have demonstrated a role for telomerase in driving tumor progression, but its mechanism of action remains unclear. Here we show that stable, ribozyme-mediated suppression of mouse...
Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
Zhou, Yamei, Yau, Christina, Gray, Joe W, Chew, Karen, Dairkee, Shanaz H, Moore, Dan H, ...
Korkola, James E, Blaveri, Ekaterina, DeVries, Sandy, Moore, Dan H, Hwang, E Shelley, Chen, Yunn-Yi, ...
Willenbucher, Robert F., Aust, Daniela E., Chang, Cornell G., Zelman, Suzanne J., Ferrell, Linda D., Moore, Dan H., ...
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon associated with a high risk of colorectal cancer. This increased cancer risk is thought to result from the cellular damage...
Aging impacts transcriptomes but not genomes of hormone-dependent breast cancers
Yau, Christina, Fedele, Vita, Roydasgupta, Ritu, Fridlyand, Jane, Hubbard, Alan, Gray, Joe W, ...
Treffers, Henry P., Moore, Dan H., Heidelberger, Michael
1. Rabbit antisera to a Type II pneumococcus specific precipitate from horse serum were tested with fractions prepared by ultracentrifugation and electrophoresis of normal and immune horse serum. 2....
ELECTROPHORETIC STUDY OF ANTIVIRAL SERA
Koprowski, Hilary, Richmond, Gilbert, Moore, Dan H.
1. Sera of animals immunized against Japanese B encephalitis, Venezuelan equine encephalomyelitis, and Western equine encephalomyelitis viruses were fractionated by electrophoresis. 2....
Morgan, Councilman, Ellison, Solon A., Rose, Harry M., Moore, Dan H.
Herpes simplex virus was visualized by the electron microscope in sections of infected chorioallantoic membrane of chicken embryos. Removal of the embedding methacrylate from relatively thick...
Morgan, Councilman, Ellison, Solon A., Rose, Harry M., Moore, Dan H.
Vaccinia and fowl pox viruses were visualized by the electron microscope in sections of infected chorioallantoic membrane of chicken embryos. The viruses were of similar structure and size, averaging...
Friedlaender, Marlene, Moore, Dan H., Koprowski, Hilary
Evidence is presented suggesting that anopheles A virus in the Ehrlich ascites tumor cell is harbored and propagated within the endoplasmic reticulum which in this system consists of an extensive...
Friedlaender, Marlene, Moore, Dan H., Love, Robert, Brown, Ray A., Koprowski, Hilary
Sections of Ehrlich ascites tumor cells infected with anopheles A virus revealed particles in the cytoplasm, which were identified as the virus on the basis of their consistent size and internal...
STRUCTURE AND DEVELOPMENT OF VIRUSES OBSERVED IN THE ELECTRON MICROSCOPE : III. INFLUENZA VIRUS
Morgan, Councilman, Rose, Harry M., Moore, Dan H.
Rods and spheres believed to represent viral particles were observed at the free surface of entodermal cells of the chorioallantoic membrane 6 to 44 hours after infection. Although occasional short...
ELECTRON MICROSCOPE STUDY OF THE DEVELOPMENT OF THE PAPILLOMA VIRUS IN THE SKIN OF THE RABBIT
Stone, Robert S., Shope, Richard E., Moore, Dan H.
Rabbit papilloma virus seems uniquely to begin its proliferation in the nucleolus of infected cells. In cells near the germinal layer of the stratum Malpighii spherical viral bodies seem to develop...
Morgan, Councilman, Bergold, G. H., Moore, Dan H., Rose, Harry M.
Thin sections of polyhedra obtained from gipsy moth larvae infected with P. dispar virus and from silkworm larvae infected with B. mori virus revealed viral particles contained within a...
Morgan, Councilman, Howe, Calderon, Rose, Harry M., Moore, Dan H.
Representative viruses of the RI-APC group were observed with the electron microscope in thin sections of infected HeLa cells. The viral particles varied in density, were approximately 60 mµ in...
ELECTRON MICROSCOPIC AND HISTOCHEMICAL OBSERVATIONS OF MUSCLE DEGENERATION AFTER TOURNIQUET
Moore, Dan H., Ruska, Helmut, Copenhaver, Wilfred M.
As an experimental model for the different forms of muscle degeneration, injury caused by 2 hours' ischemia has been studied from 20 minutes to 16 hours after release of the tourniquet. Discoid...
THE FINE STRUCTURE OF CAPILLARIES AND SMALL ARTERIES
Details of capillary endothelia of the mammalian heart are described and compared with capillaries of other organs and tissues. Continuous invagination and pinching off of the plasma membrane to form...
ELECTRON MICROSCOPE STUDY OF MAMMALIAN CARDIAC MUSCLE CELLS
The cellular theory of heart muscle is supported by a detailed description of the intercalary discs. The discs are adjacent plasma membranes separated by an interspace while the sarcolemma appears as...
THE BASE OF THE PROXIMAL CONVOLUTED TUBULE CELLS OF RAT KIDNEY
Ruska, Helmut, Moore, Dan H., Weinstock, John
The three dimensional arrangement of the compartments on the base of proximal convoluted tubule cells of rat kidney is described. An extracellular basal labyrinth is found to be enclosed by these...
Correlation of Physical and Biological Properties of Mouse Mammary Tumor Agent
Moore, Dan H., Lasfargues, E. Y., Murray, Margaret R., Haagensen, Cushman D., Pollard, E. C.
Biophysical procedures have been used to determine the size and structure of the biologically active agent responsible for the transmission, through milk, of mouse mammary adenocarcinoma. Filtration...
Production of the Milk Agent in Cultures of Mouse Mammary Carcinoma
Lasfargues, E. Y., Moore, Dan H., Murray, Margaret R., Haagensen, Cushman D., Pollard, E. C.
Thin sections of tissue cultures grown from tumors of the RIII high-breast-cancer strain mice were studied in the electron microscope. These tissues contain an abundance of particles whose morphology...
SOME EFFECTS OF THE MICROTOME KNIFE AND ELECTRON BEAM ON METHACRYLATE-EMBEDDED THIN SECTIONS
Morgan, Councilman, Moore, Dan H., Rose, Harry M.
A technique for the examination of specimens at low electron beam intensity has been presented. Sections micrographed with this technique showed numerous knife scratches and frequently contained...