Bauer Huang, Sarah L, Saheki, Yasunori, VanHoven, Miri K, Torayama, Ichiro, Ishihara, Takeshi, Katsura, Isao, ...
Abstract Background The left and right AWC olfactory neurons in Caenorhabditis elegans differ in their functions and in their expression of chemosensory receptor genes; in each animal, one AWC...
A distributed chemosensory circuit for oxygen preference in C-elegans (2006)
Chang, Andy J, Chronis, Nikolas, Karow, David S, Marletta, Michael A, Bargmann, Cornelia I
The nematode Caenorhabditis elegans has complex, naturally variable behavioral responses to environmental oxygen, food, and other animals. C. elegans detects oxygen through soluble guanylate cyclase...
A Distributed Chemosensory Circuit for Oxygen Preference in C. elegans (2006)
Andy J. Chang, Nikolas Chronis, David S. Karow, Michael A. Marletta, Cornelia I. Bargmann
The nematode Caenorhabditis elegans has complex, naturally variable behavioral responses to environmental oxygen, food, and other animals. C. elegans detects oxygen through soluble guanylate cyclase...
High-throughput reverse genetics: RNAi screens in Caenorhabditis elegans (2001)
Abstract Two recent chromosome-wide screens for phenotypes caused by RNA-mediated interference (RNAi) in Caenorhabditis elegans have increased our understanding of essential genes in nematodes. These...
Zhang, Yinong, Chou, Joseph H., Bradley, Jonathan, Bargmann, Cornelia I., Zinn, Kai
The nematode Caenorhabditis elegans exhibits behavioral responses to many volatile odorants. Chemotaxis toward one such odorant, diacetyl (butanedione), requires the function of a seven-transmembrane...
Zallen, Jennifer A., Peckol, Erin L., Tobin, David M., Bargmann, Cornelia I.
The Caenorhabditis elegans sax-1 gene regulates several aspects of neuronal cell shape. sax-1 mutants have expanded cell bodies and ectopic neurites in many classes of neurons, suggesting that SAX-1...
Clark, Scott G., Shurland, Dixie-Lee, Meyerowitz, Elliot M., Bargmann, Cornelia I., Van Der Bliek, Alexander M.
Drosophila shibire and its mammalian homologue dynamin regulate an early step in endocytosis. We identified a Caenorhabditis elegans dynamin gene, dyn-1, based upon hybridization to the Drosophila...
Zhang, Yinong, Chou, Joseph H., Bradley, Jonathan, Bargmann, Cornelia I., Zinn, Kai
The nematode Caenorhabditis elegans exhibits behavioral responses to many volatile odorants. Chemotaxis toward one such odorant, diacetyl (butanedione), requires the function of a seven-transmembrane...
Peckol, Erin L., Troemel, Emily R., Bargmann, Cornelia I.
Changes in the environment cause both short-term and long-term changes in an animal's behavior. Here we show that specific sensory experiences cause changes in chemosensory receptor gene expression...
Wang, Rong-fu, O’Hara, Eileen B., Aldea, Marti, Bargmann, Cornelia I., Gromley, Heather, Kushner, Sidney R.
The mrsC gene of Escherichia coli is required for mRNA turnover and cell growth, and strains containing the temperature-sensitive mrsC505 allele have longer half-lives than wild-type controls for...
High-throughput reverse genetics: RNAi screens in Caenorhabditis elegans
Two recent chromosome-wide screens for phenotypes caused by RNA-mediated interference (RNAi) in Caenorhabditis elegans have increased our understanding of essential genes in nematodes. These papers...
Control of neuronal subtype identity by the C. elegans ARID protein CFI-1
Shaham, Shai, Bargmann, Cornelia I.
The Caenorhabditis elegans hermaphrodite nervous system is composed of 302 neurons that fall into at least 118 diverse classes. Here we describe cfi-1, a gene that contributes to the development of...
Liedtke, Wolfgang, Tobin, David M., Bargmann, Cornelia I., Friedman, Jeffrey M.
All animals detect osmotic and mechanical stimuli, but the molecular basis for these responses is incompletely understood. The vertebrate transient receptor potential channel vanilloid subfamily 4...
Alternative olfactory neuron fates are specified by the LIM homeobox gene lim-4
Sagasti, Alvaro, Hobert, Oliver, Troemel, Emily R., Ruvkun, Gary, Bargmann, Cornelia I.
The Caenorhabditis elegans AWA, AWB, and AWC olfactory neurons are each required for the recognition of a specific subset of volatile odorants. lim-4 mutants express an AWC reporter gene...
Homologous gene targeting in Caenorhabditis elegans by biolistic transformation
Berezikov, Eugene, Bargmann, Cornelia I., Plasterk, Ronald H. A.
Targeted homologous recombination is a powerful approach for genome manipulation that is widely used for gene alteration and knockouts in mouse and yeast. In Caenorhabditis elegans, several methods...
Chuang, Chiou-Fen, Bargmann, Cornelia I.
A stochastic lateral signaling interaction between two developing Caenorhabditis elegans AWC olfactory neurons causes them to take on asymmetric patterns of odorant receptor expression, called AWCOFF...
Tanaka-Hino, Miho, Sagasti, Alvaro, Hisamoto, Naoki, Kawasaki, Masato, Nakano, Shunji, Ninomiya-Tsuji, Jun, ...
The mitogen-activated protein kinase (MAPK) pathway is a highly conserved signaling cascade that converts extracellular signals into various outputs. In Caenorhabditis elegans, asymmetric expression...
A Distributed Chemosensory Circuit for Oxygen Preference in C. elegans
Chang, Andy J, Chronis, Nikolas, Karow, David S, Marletta, Michael A, Bargmann, Cornelia I
The nematode Caenorhabditis elegans has complex, naturally variable behavioral responses to environmental oxygen, food, and other animals. C. elegans detects oxygen through soluble guanylate cyclase...
Zallen, Jennifer A., Peckol, Erin L., Tobin, David M., Bargmann, Cornelia I.
The Caenorhabditis elegans sax-1 gene regulates several aspects of neuronal cell shape. sax-1 mutants have expanded cell bodies and ectopic neurites in many classes of neurons, suggesting that SAX-1...
Clark, Scott G., Shurland, Dixie-Lee, Meyerowitz, Elliot M., Bargmann, Cornelia I., Van Der Bliek, Alexander M.
Drosophila shibire and its mammalian homologue dynamin regulate an early step in endocytosis. We identified a Caenorhabditis elegans dynamin gene, dyn-1, based upon hybridization to the Drosophila...
Zhang, Yinong, Chou, Joseph H., Bradley, Jonathan, Bargmann, Cornelia I., Zinn, Kai
The nematode Caenorhabditis elegans exhibits behavioral responses to many volatile odorants. Chemotaxis toward one such odorant, diacetyl (butanedione), requires the function of a seven-transmembrane...
Peckol, Erin L., Troemel, Emily R., Bargmann, Cornelia I.
Changes in the environment cause both short-term and long-term changes in an animal's behavior. Here we show that specific sensory experiences cause changes in chemosensory receptor gene expression...
Wang, Rong-fu, O’Hara, Eileen B., Aldea, Marti, Bargmann, Cornelia I., Gromley, Heather, Kushner, Sidney R.
The mrsC gene of Escherichia coli is required for mRNA turnover and cell growth, and strains containing the temperature-sensitive mrsC505 allele have longer half-lives than wild-type controls for...
High-throughput reverse genetics: RNAi screens in Caenorhabditis elegans
Two recent chromosome-wide screens for phenotypes caused by RNA-mediated interference (RNAi) in Caenorhabditis elegans have increased our understanding of essential genes in nematodes. These papers...
Control of neuronal subtype identity by the C. elegans ARID protein CFI-1
Shaham, Shai, Bargmann, Cornelia I.
The Caenorhabditis elegans hermaphrodite nervous system is composed of 302 neurons that fall into at least 118 diverse classes. Here we describe cfi-1, a gene that contributes to the development of...
Liedtke, Wolfgang, Tobin, David M., Bargmann, Cornelia I., Friedman, Jeffrey M.
All animals detect osmotic and mechanical stimuli, but the molecular basis for these responses is incompletely understood. The vertebrate transient receptor potential channel vanilloid subfamily 4...
Alternative olfactory neuron fates are specified by the LIM homeobox gene lim-4
Sagasti, Alvaro, Hobert, Oliver, Troemel, Emily R., Ruvkun, Gary, Bargmann, Cornelia I.
The Caenorhabditis elegans AWA, AWB, and AWC olfactory neurons are each required for the recognition of a specific subset of volatile odorants. lim-4 mutants express an AWC reporter gene...
Homologous gene targeting in Caenorhabditis elegans by biolistic transformation
Berezikov, Eugene, Bargmann, Cornelia I., Plasterk, Ronald H. A.
Targeted homologous recombination is a powerful approach for genome manipulation that is widely used for gene alteration and knockouts in mouse and yeast. In Caenorhabditis elegans, several methods...
Chuang, Chiou-Fen, Bargmann, Cornelia I.
A stochastic lateral signaling interaction between two developing Caenorhabditis elegans AWC olfactory neurons causes them to take on asymmetric patterns of odorant receptor expression, called AWCOFF...
A circuit for navigation in Caenorhabditis elegans
Gray, Jesse M., Hill, Joseph J., Bargmann, Cornelia I.
Caenorhabditis elegans explores its environment by interrupting its forward movement with occasional turns and reversals. Turns and reversals occur at stable frequencies but irregular intervals,...
Tanaka-Hino, Miho, Sagasti, Alvaro, Hisamoto, Naoki, Kawasaki, Masato, Nakano, Shunji, Ninomiya-Tsuji, Jun, ...
The mitogen-activated protein kinase (MAPK) pathway is a highly conserved signaling cascade that converts extracellular signals into various outputs. In Caenorhabditis elegans, asymmetric expression...
A Distributed Chemosensory Circuit for Oxygen Preference in C. elegans
Chang, Andy J, Chronis, Nikolas, Karow, David S, Marletta, Michael A, Bargmann, Cornelia I
The nematode Caenorhabditis elegans has complex, naturally variable behavioral responses to environmental oxygen, food, and other animals. C. elegans detects oxygen through soluble guanylate cyclase...
Pradel, Elizabeth, Zhang, Yun, Pujol, Nathalie, Matsuyama, Tohey, Bargmann, Cornelia I., Ewbank, Jonathan J.
The nematode Caenorhabditis elegans is present in soils and composts, where it can encounter a variety of microorganisms. Some bacteria in these rich environments are innocuous food sources for C....
Bauer Huang, Sarah L, Saheki, Yasunori, VanHoven, Miri K, Torayama, Ichiro, Ishihara, Takeshi, Katsura, Isao, ...
Signor, Dawn, Wedaman, Karen P., Orozco, Jose T., Dwyer, Noelle D., Bargmann, Cornelia I., Rose, Lesilee S., ...
The heterotrimeric motor protein, kinesin-II, and its presumptive cargo, can be observed moving anterogradely at 0.7 μm/s by intraflagellar transport (IFT) within sensory cilia of chemosensory...