Constantinos Tiraidis

Kinetic and crystallographic studies on 2-(β-D-glucopyranosyl)-5-methyl-1, 3, 4-oxadiazole, -benzothiazole, and -benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site

Chrysina, Evangelia D., Kosmopoulou, Magda N., Tiraidis, Constantinos, Kardakaris, Rozina, Bischler, Nicolas, Leonidas, Demetres D., ...

In an attempt to identify leads that would enable the design of inhibitors with enhanced affinity for glycogen phosphorylase (GP), that might control hyperglycaemia in type 2 diabetes, three new...