Conrad C. Huang

Comparison of methods for genomic localization of gene trap sequences (2006)

Harper, Courtney A, Huang, Conrad C, Stryke, Doug, Kawamoto, Michiko, Ferrin, Thomas E, Babbitt, Patricia C

Abstract Background Gene knockouts in a model organism such as mouse provide a valuable resource for the study of basic biology and human disease. Determining which gene has been inactivated by an...

Tools for integrated sequence-structure analysis with UCSF Chimera (2006)

Meng, Elaine C, Pettersen, Eric F, Couch, Gregory S, Huang, Conrad C, Ferrin, Thomas E

Abstract Background Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many programs exist...

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse (2006)

Nord, Alex S., Chang, Patricia J., Conklin, Bruce R., Cox, Antony V., Harper, Courtney A., Hicks, Geoffrey G., ...

Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional mutations in known and novel genes. A number of international groups have used this approach to...

The Object Technology Framework (otf): An (2002)

Gregory S. Couch, Conrad C. Huang, Eric F. Pettersen, Thomas E. Ferrin, Allison E. Howard, Teri E. Klein

This paper describes the OTF software system developed at the University of California, San Francisco Computer Graphics Laboratory for creating powerful C++ classes that facilitate rapid biomolecular...

Natural variation in human membrane transporter genes reveals evolutionary and functional constraints

Leabman, Maya K., Huang, Conrad C., DeYoung, Joseph, Carlson, Elaine J., Taylor, Travis R., De La Cruz, Melanie, ...

Membrane transporters maintain cellular and organismal homeostasis by importing nutrients and exporting toxic compounds. Transporters also play a crucial role in drug response, serving as drug...

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

Shu, Yan, Leabman, Maya K., Feng, Bo, Mangravite, Lara M., Huang, Conrad C., Stryke, Doug, ...

The organic cation transporter, OCT1, is a major hepatic transporter that mediates the uptake of many organic cations from the blood into the liver where the compounds may be metabolized or secreted...

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Stryke, Doug, Kawamoto, Michiko, Huang, Conrad C., Johns, Susan J., King, Leslie A., Harper, Courtney A., ...

The BayGenomics gene-trap resource (http://baygenomics.ucsf.edu) provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in...

The Structure Superposition Database

Chiang, Ranyee A., Meng, Elaine C., Huang, Conrad C., Ferrin, Thomas E., Babbitt, Patricia C.

The need for new tools for investigating biological systems on a large scale is becoming acute, particularly with respect to computationally intensive analyses such as comparisons of many...

MODBASE, a database of annotated comparative protein structure models, and associated resources

Pieper, Ursula, Eswar, Narayanan, Braberg, Hannes, Madhusudhan, M. S., Davis, Fred P., Stuart, Ashley C., ...

MODBASE (http://salilab.org/modbase) is a relational database of annotated comparative protein structure models for all available protein sequences matched to at least one known protein structure....

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

Nord, Alex S., Chang, Patricia J., Conklin, Bruce R., Cox, Antony V., Harper, Courtney A., Hicks, Geoffrey G., ...

Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional mutations in known and novel genes. A number of international groups have used this approach to...

Natural variation in human membrane transporter genes reveals evolutionary and functional constraints

Leabman, Maya K., Huang, Conrad C., DeYoung, Joseph, Carlson, Elaine J., Taylor, Travis R., De La Cruz, Melanie, ...

Membrane transporters maintain cellular and organismal homeostasis by importing nutrients and exporting toxic compounds. Transporters also play a crucial role in drug response, serving as drug...

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

Shu, Yan, Leabman, Maya K., Feng, Bo, Mangravite, Lara M., Huang, Conrad C., Stryke, Doug, ...

The organic cation transporter, OCT1, is a major hepatic transporter that mediates the uptake of many organic cations from the blood into the liver where the compounds may be metabolized or secreted...

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Stryke, Doug, Kawamoto, Michiko, Huang, Conrad C., Johns, Susan J., King, Leslie A., Harper, Courtney A., ...

The BayGenomics gene-trap resource (http://baygenomics.ucsf.edu) provides researchers with access to thousands of mouse embryonic stem (ES) cell lines harboring characterized insertional mutations in...

The Structure Superposition Database

Chiang, Ranyee A., Meng, Elaine C., Huang, Conrad C., Ferrin, Thomas E., Babbitt, Patricia C.

The need for new tools for investigating biological systems on a large scale is becoming acute, particularly with respect to computationally intensive analyses such as comparisons of many...

MODBASE, a database of annotated comparative protein structure models, and associated resources

Pieper, Ursula, Eswar, Narayanan, Braberg, Hannes, Madhusudhan, M. S., Davis, Fred P., Stuart, Ashley C., ...

MODBASE (http://salilab.org/modbase) is a relational database of annotated comparative protein structure models for all available protein sequences matched to at least one known protein structure....

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

Nord, Alex S., Chang, Patricia J., Conklin, Bruce R., Cox, Antony V., Harper, Courtney A., Hicks, Geoffrey G., ...

Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional mutations in known and novel genes. A number of international groups have used this approach to...