Connie Holm

Mitotic Chromosome Condensation Requires Brn1p, the Yeast Homologue of Barren

Lavoie, Brigitte D., Tuffo, K. Michelle, Oh, Scott, Koshland, Doug, Holm, Connie

In vitro studies suggest that the Barren protein may function as an activator of DNA topoisomerase II and/or as a component of the Xenopus condensin complex. To better understand the role of Barren...

Saccharomyces cerevisiae pol30 (Proliferating Cell Nuclear Antigen) Mutations Impair Replication Fidelity and Mismatch Repair

Chen, Clark, Merrill, Bradley J., Lau, Patrick J., Holm, Connie, Kolodner, Richard D.

To understand the role of POL30 in mutation suppression, 11 Saccharomyces cerevisiae pol30 mutator mutants were characterized. These mutants were grouped based on their mutagenic defects. Many pol30...

The Function of DNA Polymerase α at Telomeric G Tails Is Important for Telomere Homeostasis

Martin, Aegina Adams, Dionne, Isabelle, Wellinger, Raymund J., Holm, Connie

Telomere length control is influenced by several factors, including telomerase, the components of telomeric chromatin structure, and the conventional replication machinery. Although known components...

Mitotic Chromosome Condensation Requires Brn1p, the Yeast Homologue of Barren

Lavoie, Brigitte D., Tuffo, K. Michelle, Oh, Scott, Koshland, Doug, Holm, Connie

In vitro studies suggest that the Barren protein may function as an activator of DNA topoisomerase II and/or as a component of the Xenopus condensin complex. To better understand the role of Barren...

Saccharomyces cerevisiae pol30 (Proliferating Cell Nuclear Antigen) Mutations Impair Replication Fidelity and Mismatch Repair

Chen, Clark, Merrill, Bradley J., Lau, Patrick J., Holm, Connie, Kolodner, Richard D.

To understand the role of POL30 in mutation suppression, 11 Saccharomyces cerevisiae pol30 mutator mutants were characterized. These mutants were grouped based on their mutagenic defects. Many pol30...

The Function of DNA Polymerase α at Telomeric G Tails Is Important for Telomere Homeostasis

Martin, Aegina Adams, Dionne, Isabelle, Wellinger, Raymund J., Holm, Connie

Telomere length control is influenced by several factors, including telomerase, the components of telomeric chromatin structure, and the conventional replication machinery. Although known components...