Christer Wernstedt

p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils. (2004)

Alvarado-Kristensson, Maria, Melander, Fredrik, Leandersson, Karin, Rönnstrand, Lars, Wernstedt, Christer, Andersson, Tommy

Neutrophil apoptosis occurs both in the bloodstream and in the tissue and is considered essential for the resolution of an inflammatory process. Here, we show that p38–mitogen-activated protein...

Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin EP4-R essential for agonist-induced beta-arrestin1 recruitment that differs from the apparent principal phosphorylation site. (2004)

Neuschäfer-Rube, Frank, Hermosilla, Ricardo, Rehwald, Mathias, Rönnstrand, Lars, Schülein, Ralf, Wernstedt, Christer, ...

hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a Gs-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend on...

Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk. (2003)

Lennartsson, Johan, Wernstedt, Christer, Engström, Ulla, Hellman, Ulf, Rönnstrand, Lars

Abstract is not available

B12-dependent ribonucleotide reductases from deeply rooted eubacteria are structurally related to the aerobic enzyme from Escherichia coli

Jordan, Albert, Torrents, Eduard, Jeanthon, Christian, Eliasson, Rolf, Hellman, Ulf, Wernstedt, Christer, ...

The ribonucleotide reductases from three ancient eubacteria, the hyperthermophilic Thermotoga maritima (TM), the radioresistant Deinococcus radiodurans (DR), and the thermophilic photosynthetic...

Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

Groth, Anja, Lukas, Jiri, Nigg, Erich A., Silljé, Herman H.W., Wernstedt, Christer, Bartek, Jiri, ...

All eukaryotes respond to DNA damage by modulation of diverse cellular processes to preserve genomic integrity and ensure survival. Here we identify mammalian Tousled like kinases (Tlks) as a novel...

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis

Matsumoto, Taro, Bohman, Svante, Dixelius, Johan, Berge, Tone, Dimberg, Anna, Magnusson, Peetra, ...

Vascular endothelial growth factor receptor-2 (VEGFR-2) activation by VEGF-A is essential in vasculogenesis and angiogenesis. We have generated a pan-phosphorylation site map of VEGFR-2 and...

Echinococcus granulosus antigen 5 is closely related to proteases of the trypsin family.

Lorenzo, Carmen, Salinas, Gustavo, Brugnini, Andreina, Wernstedt, Christer, Hellman, Ulf, González-Sapienza, Gualberto

Antigen 5 (Ag5) is a dominant secreted component of the larval stage of Echinococcus granulosus, and is highly immunogenic in human infections. Although the diagnostic value of Ag5 has been...

Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site.

Neuschäfer-Rube, Frank, Hermosilla, Ricardo, Rehwald, Mathias, Rönnstrand, Lars, Schülein, Ralf, Wernstedt, Christer, ...

hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a G(s)-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend...

Phosphoproteome Profiling of Transforming Growth Factor (TGF)-β Signaling: Abrogation of TGFβ1-dependent Phosphorylation of Transcription Factor-II-I (TFII-I) Enhances Cooperation of TFII-I and Smad3 in TranscriptionD⃞

Stasyk, Taras, Dubrovska, Anna, Lomnytska, Marta, Yakymovych, Ihor, Wernstedt, Christer, Heldin, Carl-Henrik, ...

Transforming growth factor-β (TGFβ) signaling involves activation of a number of signaling pathways, several of which are controlled by phosphorylation events. Here, we describe a phosphoproteome...

B12-dependent ribonucleotide reductases from deeply rooted eubacteria are structurally related to the aerobic enzyme from Escherichia coli

Jordan, Albert, Torrents, Eduard, Jeanthon, Christian, Eliasson, Rolf, Hellman, Ulf, Wernstedt, Christer, ...

The ribonucleotide reductases from three ancient eubacteria, the hyperthermophilic Thermotoga maritima (TM), the radioresistant Deinococcus radiodurans (DR), and the thermophilic photosynthetic...

Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

Groth, Anja, Lukas, Jiri, Nigg, Erich A., Silljé, Herman H.W., Wernstedt, Christer, Bartek, Jiri, ...

All eukaryotes respond to DNA damage by modulation of diverse cellular processes to preserve genomic integrity and ensure survival. Here we identify mammalian Tousled like kinases (Tlks) as a novel...

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis

Matsumoto, Taro, Bohman, Svante, Dixelius, Johan, Berge, Tone, Dimberg, Anna, Magnusson, Peetra, ...

Vascular endothelial growth factor receptor-2 (VEGFR-2) activation by VEGF-A is essential in vasculogenesis and angiogenesis. We have generated a pan-phosphorylation site map of VEGFR-2 and...

Echinococcus granulosus antigen 5 is closely related to proteases of the trypsin family.

Lorenzo, Carmen, Salinas, Gustavo, Brugnini, Andreina, Wernstedt, Christer, Hellman, Ulf, González-Sapienza, Gualberto

Antigen 5 (Ag5) is a dominant secreted component of the larval stage of Echinococcus granulosus, and is highly immunogenic in human infections. Although the diagnostic value of Ag5 has been...

Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin receptor EP4 that is essential for agonist-induced beta-arrestin1 recruitment but differs from the apparent principal phosphorylation site.

Neuschäfer-Rube, Frank, Hermosilla, Ricardo, Rehwald, Mathias, Rönnstrand, Lars, Schülein, Ralf, Wernstedt, Christer, ...

hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a G(s)-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend...

Phosphoproteome Profiling of Transforming Growth Factor (TGF)-β Signaling: Abrogation of TGFβ1-dependent Phosphorylation of Transcription Factor-II-I (TFII-I) Enhances Cooperation of TFII-I and Smad3 in TranscriptionD⃞

Stasyk, Taras, Dubrovska, Anna, Lomnytska, Marta, Yakymovych, Ihor, Wernstedt, Christer, Heldin, Carl-Henrik, ...

Transforming growth factor-β (TGFβ) signaling involves activation of a number of signaling pathways, several of which are controlled by phosphorylation events. Here, we describe a phosphoproteome...

p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils

Alvarado-Kristensson, Maria, Melander, Fredrik, Leandersson, Karin, Rönnstrand, Lars, Wernstedt, Christer, Andersson, Tommy

Neutrophil apoptosis occurs both in the bloodstream and in the tissue and is considered essential for the resolution of an inflammatory process. Here, we show that p38–mitogen-activated protein...