Christelle Anaclet

An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients. (2008)

Lin, Jian Sheng, Dauvilliers, Yves, Arnulf, Isabelle, Bastuji, Hélène, Anaclet, Christelle, Parmentier, Régis, ...

Narcolepsy is characterized by excessive daytime sleepiness (EDS), cataplexy, direct onsets of rapid eye movement (REM) sleep from wakefulness (DREMs) and deficiency of orexins, neuropeptides that...

An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients. (2008)

Lin, Jian Sheng, Dauvilliers, Yves, Arnulf, Isabelle, Bastuji, Hélène, Anaclet, Christelle, Parmentier, Régis, ...

Narcolepsy is characterized by excessive daytime sleepiness (EDS), cataplexy, direct onsets of rapid eye movement (REM) sleep from wakefulness (DREMs) and deficiency of orexins, neuropeptides that...

The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders. (2007)

Parmentier, Régis, Anaclet, Christelle, Guhennec, Christian, Brousseau, Emmanuel, Bricout, Denis, Giboulot, Thierry, ...

Brain histaminergic neurons play a prominent role in arousal and maintenance of wakefulness (W). H(3)-receptors control the activity of histaminergic neurons through presynaptic autoinhibition. The...

Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649. (2007)

Ligneau, Xavier, Landais, Laurent, Perrin, David, Piriou, Johanne, Uguen, Marilyne, Denis, Emmanuel, ...

BF2.649, a high affinity and selective non-imidazole histamine H(3)-receptor antagonist/inverse agonist, was found to easily enter the brain after oral administration to mice: it displayed a ratio of...

The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders. (2007)

Parmentier, Régis, Anaclet, Christelle, Guhennec, Christian, Brousseau, Emmanuel, Bricout, Denis, Giboulot, Thierry, ...

Brain histaminergic neurons play a prominent role in arousal and maintenance of wakefulness (W). H(3)-receptors control the activity of histaminergic neurons through presynaptic autoinhibition. The...

Brain histamine and schizophrenia: potential therapeutic applications of H3-receptor inverse agonists studied with BF2.649. (2007)

Ligneau, Xavier, Landais, Laurent, Perrin, David, Piriou, Johanne, Uguen, Marilyne, Denis, Emmanuel, ...

BF2.649, a high affinity and selective non-imidazole histamine H(3)-receptor antagonist/inverse agonist, was found to easily enter the brain after oral administration to mice: it displayed a ratio of...