Chengquan Zhao

RL-37, an Alpha-Helical Antimicrobial Peptide of the Rhesus Monkey

Zhao, Chengquan, Nguyen, Tung, Boo, Lee Ming, Hong, Teresa, Espiritu, Cesar, Orlov, Dmitri, ...

Rhesus monkey bone marrow expresses a cathelicidin whose C-terminal domain comprises a 37-residue alpha-helical peptide (RL-37) that resembles human LL-37. Like its human counterpart, RL-37 rapidly...

Purification and Properties of Proline-Rich Antimicrobial Peptides from Sheep and Goat Leukocytes

Shamova, Olga, Brogden, Kim A., Zhao, Chengquan, Nguyen, Tung, Kokryakov, Vladimir N., Lehrer, Robert I.

We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5α and ChBac5, to detailed analysis. OaBac5α and...

Differential Expression of Caprine β-Defensins in Digestive and Respiratory Tissues

Zhao, Chengquan, Nguyen, Tung, Liu, Lide, Shamova, Olga, Brogden, Kim, Lehrer, Robert I.

We identified two novel β-defensin precursors, preproGBD-1 and preproGBD-2, in the tissues of a goat. Although the precursors were identical in 96.8% of their bases and 88.2% (60 of 68) of their...

Gallinacin-3, an Inducible Epithelial β-Defensin in the Chicken

Zhao, Chengquan, Nguyen, Tung, Liu, Lide, Sacco, Randy E., Brogden, Kim A., Lehrer, Robert I.

Gallinacin-3 and gallopavin-1 (GPV-1) are newly characterized, epithelial β-defensins of the chicken (Gallus gallus) and turkey (Meleagris gallopavo), respectively. In normal chickens, the...

Retrocyclin: A primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1

Cole, Alexander M., Hong, Teresa, Boo, Lee Ming, Nguyen, Tung, Zhao, Chengquan, Bristol, Greg, ...

Human bone marrow expresses a pseudogene that encodes an antimicrobial peptide homologous to rhesus monkey circular minidefensins (θ-defensins). We prepared the putative ancestral human peptide by...

RL-37, an Alpha-Helical Antimicrobial Peptide of the Rhesus Monkey

Zhao, Chengquan, Nguyen, Tung, Boo, Lee Ming, Hong, Teresa, Espiritu, Cesar, Orlov, Dmitri, ...

Rhesus monkey bone marrow expresses a cathelicidin whose C-terminal domain comprises a 37-residue alpha-helical peptide (RL-37) that resembles human LL-37. Like its human counterpart, RL-37 rapidly...

Purification and Properties of Proline-Rich Antimicrobial Peptides from Sheep and Goat Leukocytes

Shamova, Olga, Brogden, Kim A., Zhao, Chengquan, Nguyen, Tung, Kokryakov, Vladimir N., Lehrer, Robert I.

We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5α and ChBac5, to detailed analysis. OaBac5α and...

Differential Expression of Caprine β-Defensins in Digestive and Respiratory Tissues

Zhao, Chengquan, Nguyen, Tung, Liu, Lide, Shamova, Olga, Brogden, Kim, Lehrer, Robert I.

We identified two novel β-defensin precursors, preproGBD-1 and preproGBD-2, in the tissues of a goat. Although the precursors were identical in 96.8% of their bases and 88.2% (60 of 68) of their...

Gallinacin-3, an Inducible Epithelial β-Defensin in the Chicken

Zhao, Chengquan, Nguyen, Tung, Liu, Lide, Sacco, Randy E., Brogden, Kim A., Lehrer, Robert I.

Gallinacin-3 and gallopavin-1 (GPV-1) are newly characterized, epithelial β-defensins of the chicken (Gallus gallus) and turkey (Meleagris gallopavo), respectively. In normal chickens, the...

Retrocyclin: A primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1

Cole, Alexander M., Hong, Teresa, Boo, Lee Ming, Nguyen, Tung, Zhao, Chengquan, Bristol, Greg, ...

Human bone marrow expresses a pseudogene that encodes an antimicrobial peptide homologous to rhesus monkey circular minidefensins (θ-defensins). We prepared the putative ancestral human peptide by...