Functional genomic delineation of TLR-induced transcriptional networks (2007)
Elkon, Ran, Linhart, Chaim, Halperin, Yonit, Shiloh, Yosef, Shamir, Ron
Abstract Background The innate immune system is the first line of defense mechanisms protecting the host from invading pathogens such as bacteria and viruses. The innate immunity responses are...
EXPANDER– an integrative program suite for microarray data analysis (2005)
Shamir, Ron, Maron-Katz, Adi, Tanay, Amos, Linhart, Chaim, Steinfeld, Israel, Sharan, Roded, ...
Abstract Background Gene expression microarrays are a prominent experimental tool in functional genomics which has opened the opportunity for gaining global, systems-level understanding of...
Elkon, Ran, Rashi-Elkeles, Sharon, Lerenthal, Yaniv, Linhart, Chaim, Tenne, Tamar, Amariglio, Ninette, ...
Abstract Background Gene-expression microarrays and RNA interferences (RNAi) are among the most prominent techniques in functional genomics. The combination of the two holds promise for systematic,...
The Canine Olfactory Subgenome (2004)
Tania Fuchs, Chaim Linhart, Ron Shamir, Mark Adams, Francis Kalush, Miriam Khen
We identified 971 olfactory receptor (OR) genes in the dog genome, estimated to constitute f80% of the canine OR repertoire. This was achieved by directed genomic DNA cloning of olfactory sequence...
Ran Elkon, Chaim Linhart, Roded Sharan, Ron Shamir
Dissection of regulatory networks that control gene transcription is one of the greatest challenges of functional genomics. By utilizing human genomic sequences, models for binding sites of known...
A PCR primer sequence is called degenerate if some of its positions have several possible bases. The degeneracy of the primer is the number of unique sequence combinations it contains. We study the...
DEFOG: A Practical Scheme for Deciphering Families of Genes (2002)
Fuchs,Tania, Malecova,Barbora, Linhart,Chaim, Sharan,Roded, Khen,Miriam, Herwig,Ralf, ...
We developed a novel efficient scheme, DEFOG (for "deciphering families of genes"), for determining sequences of numerous genes from a family of interest. The scheme provides a powerful means to...
DEFOG: A Practical Scheme for Deciphering Families of Genes (2002)
Fuchs, Tania, Malecova, Barbora, Linhart, Chaim, Sharan, Roded, Khen, Miriam, Herwig, Ralf, ...
We developed a novel efficient scheme, DEFOG (for "deciphering families of genes"), for determining sequences of numerous genes from a family of interest. The scheme provides a powerful means to...
On-line Zone Construction in Arrangements of Lines in the Plane (2000)
Chaim Linhart, Dan Halperin, Sariel Har-peled
Given a nite set L of lines in the plane we wish to compute the zone of an additional curve in the arrangement A(L), namely the set of faces of the planar subdivision induced by the lines in L that...
On-line Zone Construction in Arrangements of Lines in the Plane (1999)
Yuval Aharoni, Dan Halperin, Iddo Hanniel, Sariel Har-peled, Chaim Linhart
. Given a nite set L of lines in the plane we wish to compute the zone of an additional curve in the arrangement A(L), namely the set of faces of the planar subdivision induced by the lines in L that...
CGAL - Smallest Enclosing Circle with Polygonal Obstacles ( Min_circle_obstacles_2 ) (1999)
. Given a set S of points in the plane and a set P of polygons (obstacles), we wish to nd a disc of radius r that covers S and whose center is not inside one of the polygons in P , as well as to...
On-line Zone Construction in Arrangements of Lines in the Plane (1999)
Yuval Aharoni, Dan Halperin, Iddo Hanniel, Sariel Har-peled, Chaim Linhart
. Given a nite set L of lines in the plane we wish to compute the zone of an additional curve in the arrangement A(L), namely the set of faces of the planar subdivision induced by the lines in L that...
Elkon, Ran, Linhart, Chaim, Sharan, Roded, Shamir, Ron, Shiloh, Yosef
Dissection of regulatory networks that control gene transcription is one of the greatest challenges of functional genomics. Using human genomic sequences, models for binding sites of known...
In silico identification of transcriptional regulators associated with c-Myc
Elkon, Ran, Zeller, Karen I., Linhart, Chaim, Dang, Chi V., Shamir, Ron, Shiloh, Yosef
The development of powerful experimental strategies for functional genomics and accompanying computational tools has brought major advances in the delineation of transcriptional networks in organisms...
Elkon, Ran, Rashi-Elkeles, Sharon, Lerenthal, Yaniv, Linhart, Chaim, Tenne, Tamar, Amariglio, Ninette, ...
Microarray and RNAi technologies were applied to dissect a transcriptional network induced by DNA damage in human cells, revealing that two pivotal stress-induced transcription factors (NFκB and...
EXPANDER – an integrative program suite for microarray data analysis
Shamir, Ron, Maron-Katz, Adi, Tanay, Amos, Linhart, Chaim, Steinfeld, Israel, Sharan, Roded, ...
Elkon, Ran, Linhart, Chaim, Sharan, Roded, Shamir, Ron, Shiloh, Yosef
Dissection of regulatory networks that control gene transcription is one of the greatest challenges of functional genomics. Using human genomic sequences, models for binding sites of known...
In silico identification of transcriptional regulators associated with c-Myc
Elkon, Ran, Zeller, Karen I., Linhart, Chaim, Dang, Chi V., Shamir, Ron, Shiloh, Yosef
The development of powerful experimental strategies for functional genomics and accompanying computational tools has brought major advances in the delineation of transcriptional networks in organisms...
Elkon, Ran, Rashi-Elkeles, Sharon, Lerenthal, Yaniv, Linhart, Chaim, Tenne, Tamar, Amariglio, Ninette, ...
Microarray and RNAi technologies were applied to dissect a transcriptional network induced by DNA damage in human cells, revealing that two pivotal stress-induced transcription factors (NFκB and...