Carole Alies

Mutation of exposed hydrophobic amino acids to arginine to increase protein stability (2004)

Strub, Caroline, Alies, Carole, Lougarre, Andrée, Ladurantie, Caroline, Czaplicki, Jerzy, Fournier, Didier

Abstract Background One strategy to increase the stability of proteins is to reduce the area of water-accessible hydrophobic surface. Results In order to test it, we replaced 14 solvent-exposed...

Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance (2004)

Shi, Ming, Lougarre, Andrée, Alies, Carole, Frémaux, Isabelle, Tang, Zhen, Stojan, Jure, ...

Abstract Background Insecticide resistance is now common in insects due to the frequent use of chemicals to control them, which provides a useful tool to study the adaptation of eukaryotic genome to...