Carl Mann

Data Reduction of Airborne Sensor Records. (2002)

Bradie,Richard A., Bay,Alex, Biache,Andrew, Mann,Carl, Peppard,Clinton

The capabilities of four remote sensors - panoramic camera, thermal infrared scanner, laser profiler and side-looking airborne radar - were examined to determine level of ice detail of code,...

Saccharomyces cerevisiae MPS2 Encodes a Membrane Protein Localized at the Spindle Pole Body and the Nuclear Envelope

McBratney, Susan, Monterrosa, Antonio, Byers, Breck, Mann, Carl, Winey, Mark

The MPS2 (monopolar spindle two) gene is one of several genes required for the proper execution of spindle pole body (SPB) duplication in the budding yeast Saccharomyces cerevisiae (Winey et al.,...

Xbp1-Mediated Repression of CLB Gene Expression Contributes to the Modifications of Yeast Cell Morphology and Cell Cycle Seen during Nitrogen-Limited Growth

Miled, Chaouki, Mann, Carl, Faye, Gérard

Yeast cells undergo morphological transformations in response to diverse environmental signals. One such event, called pseudohyphal differentiation, occurs when diploid yeast cells are partially...

Sgt1p Contributes to Cyclic AMP Pathway Activity and Physically Interacts with the Adenylyl Cyclase Cyr1p/Cdc35p in Budding Yeast

Dubacq, Caroline, Guerois, Raphaël, Courbeyrette, Régis, Kitagawa, Katsumi, Mann, Carl

Sgt1p is a highly conserved eucaryotic protein that is required for both SCF (Skp1p/Cdc53p-Cullin-F-box)-mediated ubiquitination and kinetochore function in yeast. We show here that Sgt1p is also...

Silent repair accounts for cell cycle specificity in the signaling of oxidative DNA lesions

Leroy, Christophe, Mann, Carl, Marsolier, Marie-Claude

Reactive oxygen species are the most important source of DNA lesions in aerobic organisms, but little is known about the activation of the DNA checkpoints in response to oxidative stress. We show...

Specificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast

Hermand, Damien, Westerling, Thomas, Pihlak, Arno, Thuret, Jean-Yves, Vallenius, Tea, Tiainen, Marianne, ...

Activating phosphorylation of cyclin-dependent kinases (Cdks) is mediated by at least two structurally distinct types of Cdk-activating kinases (Caks): the trimeric Cdk7–cyclin H–Mat1 complex in...

Yaf9, a Novel NuA4 Histone Acetyltransferase Subunit, Is Required for the Cellular Response to Spindle Stress in Yeast

Le Masson, Ivan, Yu, David Y., Jensen, Kurt, Chevalier, Anne, Courbeyrette, Régis, Boulard, Yves, ...

Yaf9 is one of three proteins in budding yeast containing a YEATS domain. We show that Yaf9 is part of a large complex and that it coprecipitates with three known subunits of the NuA4 histone...

The Protein Kinase Snf1 Is Required for Tolerance to the Ribonucleotide Reductase Inhibitor Hydroxyurea

Dubacq, Caroline, Chevalier, Anne, Mann, Carl

The Snf1/AMP-activated kinases are involved in a wide range of stress responses in eukaryotic cells. We discovered a novel role for the Snf1 kinase in the cellular response to genotoxic stress in...

Structural basis for the interaction of Asf1 with histone H3 and its functional implications

Mousson, Florence, Lautrette, Aurélie, Thuret, Jean-Yves, Agez, Morgane, Courbeyrette, Régis, Amigues, Béatrice, ...

Asf1 is a conserved histone chaperone implicated in nucleosome assembly, transcriptional silencing, and the cellular response to DNA damage. We solved the NMR solution structure of the N-terminal...

Saccharomyces cerevisiae MPS2 Encodes a Membrane Protein Localized at the Spindle Pole Body and the Nuclear Envelope

McBratney, Susan, Monterrosa, Antonio, Byers, Breck, Mann, Carl, Winey, Mark

The MPS2 (monopolar spindle two) gene is one of several genes required for the proper execution of spindle pole body (SPB) duplication in the budding yeast Saccharomyces cerevisiae (Winey et al.,...

Xbp1-Mediated Repression of CLB Gene Expression Contributes to the Modifications of Yeast Cell Morphology and Cell Cycle Seen during Nitrogen-Limited Growth

Miled, Chaouki, Mann, Carl, Faye, Gérard

Yeast cells undergo morphological transformations in response to diverse environmental signals. One such event, called pseudohyphal differentiation, occurs when diploid yeast cells are partially...

Sgt1p Contributes to Cyclic AMP Pathway Activity and Physically Interacts with the Adenylyl Cyclase Cyr1p/Cdc35p in Budding Yeast

Dubacq, Caroline, Guerois, Raphaël, Courbeyrette, Régis, Kitagawa, Katsumi, Mann, Carl

Sgt1p is a highly conserved eucaryotic protein that is required for both SCF (Skp1p/Cdc53p-Cullin-F-box)-mediated ubiquitination and kinetochore function in yeast. We show here that Sgt1p is also...

Silent repair accounts for cell cycle specificity in the signaling of oxidative DNA lesions

Leroy, Christophe, Mann, Carl, Marsolier, Marie-Claude

Reactive oxygen species are the most important source of DNA lesions in aerobic organisms, but little is known about the activation of the DNA checkpoints in response to oxidative stress. We show...

Specificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast

Hermand, Damien, Westerling, Thomas, Pihlak, Arno, Thuret, Jean-Yves, Vallenius, Tea, Tiainen, Marianne, ...

Activating phosphorylation of cyclin-dependent kinases (Cdks) is mediated by at least two structurally distinct types of Cdk-activating kinases (Caks): the trimeric Cdk7–cyclin H–Mat1 complex in...

Yaf9, a Novel NuA4 Histone Acetyltransferase Subunit, Is Required for the Cellular Response to Spindle Stress in Yeast

Le Masson, Ivan, Yu, David Y., Jensen, Kurt, Chevalier, Anne, Courbeyrette, Régis, Boulard, Yves, ...

Yaf9 is one of three proteins in budding yeast containing a YEATS domain. We show that Yaf9 is part of a large complex and that it coprecipitates with three known subunits of the NuA4 histone...

The Protein Kinase Snf1 Is Required for Tolerance to the Ribonucleotide Reductase Inhibitor Hydroxyurea

Dubacq, Caroline, Chevalier, Anne, Mann, Carl

The Snf1/AMP-activated kinases are involved in a wide range of stress responses in eukaryotic cells. We discovered a novel role for the Snf1 kinase in the cellular response to genotoxic stress in...

Structural basis for the interaction of Asf1 with histone H3 and its functional implications

Mousson, Florence, Lautrette, Aurélie, Thuret, Jean-Yves, Agez, Morgane, Courbeyrette, Régis, Amigues, Béatrice, ...

Asf1 is a conserved histone chaperone implicated in nucleosome assembly, transcriptional silencing, and the cellular response to DNA damage. We solved the NMR solution structure of the N-terminal...

Yeast homolog of a cancer-testis antigen defines a new transcription complex

Kisseleva-Romanova, Elena, Lopreiato, Raffaele, Baudin-Baillieu, Agnès, Rousselle, Jean-Claude, Ilan, Laila, Hofmann, Kay, ...

We have isolated a new yeast gene (PCC1) that codes for a factor homologous to human cancer-testis antigens. We provide evidence that Pcc1p is a new transcription factor and that its mutation affects...

In Vivo Study of the Nucleosome Assembly Functions of ASF1 Histone Chaperones in Human Cells▿ †

Galvani, Angélique, Courbeyrette, Régis, Agez, Morgane, Ochsenbein, Françoise, Mann, Carl, Thuret, Jean-Yves

Histone chaperones have been implicated in nucleosome assembly and disassembly as well as histone modification. ASF1 is a highly conserved histone H3/H4 chaperone that synergizes in vitro with two...