Press, Joshua Z., De Luca, Alessandro, Boyd, Niki, Young, Sean, Troussard, Armelle, Ridge, Yolanda, ...
Press, Joshua Z, De Luca, Alessandro, Boyd, Niki, Young, Sean, Troussard, Armelle, Ridge, Yolanda, ...
Background Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis. Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as...
Prentice, Leah M, Klausen, Christian, Kalloger, Steve, Köbel, Martin, McKinney, Steven, Santos, Jennifer L, ...
Abstract Background Kisspeptins and their G-protein coupled receptor, GPR54 are required for GnRH release and have been associated with anti-metastatic tumour cell behaviour in model systems. The...
Kucab, Jill E, Lee, Cathy, Chen, Ching-Shih, Zhu, Jiuxiang, Gilks, C Blake, Cheang, Maggie, ...
Abstract Introduction Phosphorylated Akt (P-Akt) is an attractive molecular target because it contributes to the development of breast cancer and confers resistance to conventional therapies. Akt...
Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells
Doan, Loretta L., Porter, Susan D., Duan, Zhijun, Flubacher, Marcella M., Montoya, Diego, Tsichlis, Philip N., ...
Growth factor independence-1 (GFI1) and GFI1B are closely related, yet differentially expressed transcriptional repressors with nearly identical DNA binding domains. GFI1 is upregulated in the...
Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours
Kucab, Jill E, Lee, Cathy, Chen, Ching-Shih, Zhu, Jiuxiang, Gilks, C Blake, Cheang, Maggie, ...
West, Robert B., Rubin, Brian P., Miller, Melinda A., Subramanian, Subbaya, Kaygusuz, Gulsah, Montgomery, Kelli, ...
Tenosynovial giant-cell tumor (TGCT) and pigmented villonodular synovitis (PVNS) are related conditions with features of both reactive inflammatory disorders and clonal neoplastic proliferations....
Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells
Doan, Loretta L., Porter, Susan D., Duan, Zhijun, Flubacher, Marcella M., Montoya, Diego, Tsichlis, Philip N., ...
Growth factor independence-1 (GFI1) and GFI1B are closely related, yet differentially expressed transcriptional repressors with nearly identical DNA binding domains. GFI1 is upregulated in the...
Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours
Kucab, Jill E, Lee, Cathy, Chen, Ching-Shih, Zhu, Jiuxiang, Gilks, C Blake, Cheang, Maggie, ...
West, Robert B., Rubin, Brian P., Miller, Melinda A., Subramanian, Subbaya, Kaygusuz, Gulsah, Montgomery, Kelli, ...
Tenosynovial giant-cell tumor (TGCT) and pigmented villonodular synovitis (PVNS) are related conditions with features of both reactive inflammatory disorders and clonal neoplastic proliferations....
Liu, Chih Long, Prapong, Wijan, Natkunam, Yasodha, Alizadeh, Ash, Montgomery, Kelli, Gilks, C. Blake, ...
The creation of tissue microarrays (TMAs) allows for the rapid immunohistochemical analysis of thousands of tissue samples, with numerous different antibodies per sample. This technical development...
Nielsen, Torsten O., Hsu, Forrest D., O’Connell, John X., Gilks, C. Blake, Sorensen, Poul H.B., Linn, Sabine, ...
Histological diagnosis of synovial sarcoma can be difficult. Genome-wide expression profiling has identified a number of genes expressed at higher levels in synovial sarcoma than in other soft tissue...
Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans
Linn, Sabine C., West, Rob B., Pollack, Jonathan R., Zhu, Shirley, Hernandez-Boussard, Tina, Nielsen, Torsten O., ...
Dermatofibrosarcoma protuberans (DFSP) is an aggressive spindle cell neoplasm. It is associated with the chromosomal translocation, t(17:22), which fuses the COL1A1 and PDGFβ genes. We determined...
Rajput, Ashish B., Turbin, Dmitry A., Cheang, Maggie CU, Voduc, David K., Leung, Sam, Gelmon, Karen A., ...
Prentice, Leah M, Klausen, Christian, Kalloger, Steve, Köbel, Martin, McKinney, Steven, Santos, Jennifer L, ...