Valentin, Guillaume, Verheggen, Céline, Piolot, Tristan, Neel, Henry, Coppey-Moisan, Maïté, Bertrand, Edouard
Initiation of Nucleolar Assembly Is Independent of RNA Polymerase I Transcription
Dousset, Thibaut, Wang, Chen, Verheggen, Céline, Chen, Danyang, Hernandez-Verdun, Danièle, Huang, Sui
This report examines the distribution of an RNA polymerase I transcription factor (upstream binding factor; UBF), pre-rRNA processing factors (nucleolin and fibrillarin), and pre-rRNAs throughout...
Verheggen, Céline, Mouaikel, John, Thiry, Marc, Blanchard, Jean-Marie, Tollervey, David, Bordonné, Remi, ...
Nucleolar localization of box C/D small nucleolar (sno) RNAs requires the box C/D motif and, in vertebrates, involves transit through Cajal bodies (CB). We report that in yeast, overexpression of a...
Darzacq, Xavier, Jády, Beáta E., Verheggen, Céline, Kiss, Arnold M., Bertrand, Edouard, Kiss, Tamás
Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their...
Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments
Verheggen, Céline, Lafontaine, Denis L.J., Samarsky, Dmitry, Mouaikel, John, Blanchard, Jean-Marie, Bordonné, Rémy, ...
Nucleolar localization of vertebrate box C/D snoRNA involves transit through Cajal bodies, but the significance of this event is unkown. To define better the function of this compartment, we analyzed...
A Cajal body-specific pseudouridylation guide RNA is composed of two box H/ACA snoRNA-like domains
Kiss, Arnold M., Jády, Beáta E., Darzacq, Xavier, Verheggen, Céline, Bertrand, Edouard, Kiss, Tamás
Site-specific post-transcriptional conversion of uridines to pseudouridine in ribosomal RNAs and small nuclear RNAs (snRNAs) is directed by guide RNAs which possess the conserved box H and ACA...
A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs
Richard, Patricia, Darzacq, Xavier, Bertrand, Edouard, Jády, Beáta E., Verheggen, Céline, Kiss, Tamás
Post-transcriptional synthesis of 2′-O-methylated nucleotides and pseudouridines in Sm spliceosomal small nuclear RNAs takes place in the nucleoplasmic Cajal bodies and it is directed by guide RNAs...
Mouaikel, John, Narayanan, Usha, Verheggen, Céline, Matera, A. Gregory, Bertrand, Edouard, Tazi, Jamal, ...
The biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) requires the cytoplasmic assembly of the Sm-core complex, followed by the hypermethylation of the small nuclear RNA (snRNA)...
Initiation of Nucleolar Assembly Is Independent of RNA Polymerase I Transcription
Dousset, Thibaut, Wang, Chen, Verheggen, Céline, Chen, Danyang, Hernandez-Verdun, Danièle, Huang, Sui
This report examines the distribution of an RNA polymerase I transcription factor (upstream binding factor; UBF), pre-rRNA processing factors (nucleolin and fibrillarin), and pre-rRNAs throughout...
Verheggen, Céline, Mouaikel, John, Thiry, Marc, Blanchard, Jean-Marie, Tollervey, David, Bordonné, Remi, ...
Nucleolar localization of box C/D small nucleolar (sno) RNAs requires the box C/D motif and, in vertebrates, involves transit through Cajal bodies (CB). We report that in yeast, overexpression of a...
Darzacq, Xavier, Jády, Beáta E., Verheggen, Céline, Kiss, Arnold M., Bertrand, Edouard, Kiss, Tamás
Cajal (coiled) bodies are conserved subnuclear organelles that are present in the nucleoplasm of both animal and plant cells. Although Cajal bodies were first described nearly 100 years ago, their...
Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments
Verheggen, Céline, Lafontaine, Denis L.J., Samarsky, Dmitry, Mouaikel, John, Blanchard, Jean-Marie, Bordonné, Rémy, ...
Nucleolar localization of vertebrate box C/D snoRNA involves transit through Cajal bodies, but the significance of this event is unkown. To define better the function of this compartment, we analyzed...
A Cajal body-specific pseudouridylation guide RNA is composed of two box H/ACA snoRNA-like domains
Kiss, Arnold M., Jády, Beáta E., Darzacq, Xavier, Verheggen, Céline, Bertrand, Edouard, Kiss, Tamás
Site-specific post-transcriptional conversion of uridines to pseudouridine in ribosomal RNAs and small nuclear RNAs (snRNAs) is directed by guide RNAs which possess the conserved box H and ACA...
A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs
Richard, Patricia, Darzacq, Xavier, Bertrand, Edouard, Jády, Beáta E., Verheggen, Céline, Kiss, Tamás
Post-transcriptional synthesis of 2′-O-methylated nucleotides and pseudouridines in Sm spliceosomal small nuclear RNAs takes place in the nucleoplasmic Cajal bodies and it is directed by guide RNAs...
Mouaikel, John, Narayanan, Usha, Verheggen, Céline, Matera, A. Gregory, Bertrand, Edouard, Tazi, Jamal, ...
The biogenesis of spliceosomal small nuclear ribonucleoproteins (snRNPs) requires the cytoplasmic assembly of the Sm-core complex, followed by the hypermethylation of the small nuclear RNA (snRNA)...
Verheggen, Céline, Le Panse, Sophie, Almouzni, Geneviève, Hernandez-Verdun, Danièle
During the early development of Xenopus laevis, we followed in individual nuclei the formation of a nucleolus by examining simultaneously its structural organization and its transcriptional...
Verheggen, Céline, Almouzni, Geneviève, Hernandez-Verdun, Danièle
Transcription and splicing of messenger RNAs are temporally and spatially coordinated through the recruitment by RNA polymerase II of processing factors. We questioned whether RNA polymerase I plays...
The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery
Boulon, Séverine, Marmier-Gourrier, Nathalie, Pradet-Balade, Bérengère, Wurth, Laurence, Verheggen, Céline, Jády, Beáta E., ...
RNA-binding proteins of the L7Ae family are at the heart of many essential ribonucleoproteins (RNPs), including box C/D and H/ACA small nucleolar RNPs, U4 small nuclear RNP, telomerase, and messenger...