Buzz Baum

A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila (2008)

Jeroen Dobbelaere, Filipe Josué, Saskia Suijkerbuijk, Buzz Baum, Nicolas Tapon, Jordan Raff

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila...

Minimizing the risk of reporting false positives in large-scale RNAi screens (2006)

Echeverri, Christophe J, Beachy, Philip A, Baum, Buzz, Boutros, Michael, Buchholz, Frank, Chanda, Sumit K, ...

Large-scale RNA interference (RNAi)-based analyses, very much as other 'omic' approaches, have inherent rates of false positives and negatives. The variability in the standards of care applied to...

FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets

Sims, David, Bursteinas, Borisas, Gao, Qiong, Zvelebil, Marketa, Baum, Buzz

FLIGHT () is a new database designed to help researchers browse and cross-correlate data from large-scale RNAi studies. To date, the majority of these functional genomic screens have been carried out...

FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets

Sims, David, Bursteinas, Borisas, Gao, Qiong, Zvelebil, Marketa, Baum, Buzz

FLIGHT () is a new database designed to help researchers browse and cross-correlate data from large-scale RNAi studies. To date, the majority of these functional genomic screens have been carried out...

The Evolution of Robust Development and Homeostasis in Artificial Organisms

Basanta, David, Miodownik, Mark, Baum, Buzz

During embryogenesis, multicellular animals are shaped via cell proliferation, cell rearrangement, and apoptosis. At the end of development, tissue architecture is then maintained through balanced...

A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila

Dobbelaere, Jeroen, Josué, Filipe, Suijkerbuijk, Saskia, Baum, Buzz, Tapon, Nicolas, Raff, Jordan

Centrosomes comprise a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Here, we have performed a microscopy-based genome-wide RNA interference (RNAi) screen in Drosophila...