Antibody Arrays Identify Potential Diagnostic Markers of Hepatocellular Carcinoma (2008)
Hongbo Sun, Mei-Sze Chua, Dorothy Yang, Anya Tsalenko, Brian J. Peter, Samuel So
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide. Effective treatment of HCC patients is hampered by the lack of sensitive and specific diagnostic markers of HCC....
Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli (2004)
Peter, Brian J, Arsuaga, Javier, Breier, Adam M, Khodursky, Arkady B, Brown, Patrick O, Cozzarelli, Nicholas R
Abstract Background The chromosome of Escherichia coli is maintained in a negatively supercoiled state, and supercoiling levels are affected by growth phase and a variety of environmental stimuli. In...
Analysis of topoisomerase function in bacterial replication fork movement: Use of DNA microarrays
Khodursky, Arkady B., Peter, Brian J., Schmid, Molly B., DeRisi, Joseph, Botstein, David, Brown, Patrick O., ...
We used DNA microarrays of the Escherichia coli genome to trace the progression of chromosomal replication forks in synchronized cells. We found that both DNA gyrase and topoisomerase IV (topo IV)...
Khodursky, Arkady B., Peter, Brian J., Cozzarelli, Nicholas R., Botstein, David, Brown, Patrick O., Yanofsky, Charles
We investigated the global changes in mRNA abundance in Escherichia coli elicited by various perturbations of tryptophan metabolism. To do so we printed DNA microarrays containing 95% of all...
Zimmer, Daniel P., Soupene, Eric, Lee, Haidy L., Wendisch, Volker F., Khodursky, Arkady B., Peter, Brian J., ...
Nitrogen regulatory protein C (NtrC) of enteric bacteria activates transcription of genes/operons whose products minimize the slowing of growth under nitrogen-limiting conditions. To reveal the NtrC...
Topological challenges to DNA replication: Conformations at the fork
Postow, Lisa, Crisona, Nancy J., Peter, Brian J., Hardy, Christine D., Cozzarelli, Nicholas R.
The unwinding of the parental DNA duplex during replication causes a positive linking number difference, or superhelical strain, to build up around the elongating replication fork. The branching at...
Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli
Peter, Brian J, Arsuaga, Javier, Breier, Adam M, Khodursky, Arkady B, Brown, Patrick O, Cozzarelli, Nicholas R
Microarray analysis shows that transcription of 306 E. Coli genes is affected by changes in the level of chromosome supercoiling, suggesting that supercoiling transmits regulatory signals from the...
Analysis of topoisomerase function in bacterial replication fork movement: Use of DNA microarrays
Khodursky, Arkady B., Peter, Brian J., Schmid, Molly B., DeRisi, Joseph, Botstein, David, Brown, Patrick O., ...
We used DNA microarrays of the Escherichia coli genome to trace the progression of chromosomal replication forks in synchronized cells. We found that both DNA gyrase and topoisomerase IV (topo IV)...
Khodursky, Arkady B., Peter, Brian J., Cozzarelli, Nicholas R., Botstein, David, Brown, Patrick O., Yanofsky, Charles
We investigated the global changes in mRNA abundance in Escherichia coli elicited by various perturbations of tryptophan metabolism. To do so we printed DNA microarrays containing 95% of all...
Zimmer, Daniel P., Soupene, Eric, Lee, Haidy L., Wendisch, Volker F., Khodursky, Arkady B., Peter, Brian J., ...
Nitrogen regulatory protein C (NtrC) of enteric bacteria activates transcription of genes/operons whose products minimize the slowing of growth under nitrogen-limiting conditions. To reveal the NtrC...
Topological challenges to DNA replication: Conformations at the fork
Postow, Lisa, Crisona, Nancy J., Peter, Brian J., Hardy, Christine D., Cozzarelli, Nicholas R.
The unwinding of the parental DNA duplex during replication causes a positive linking number difference, or superhelical strain, to build up around the elongating replication fork. The branching at...
Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli
Peter, Brian J, Arsuaga, Javier, Breier, Adam M, Khodursky, Arkady B, Brown, Patrick O, Cozzarelli, Nicholas R
Microarray analysis shows that transcription of 306 E. Coli genes is affected by changes in the level of chromosome supercoiling, suggesting that supercoiling transmits regulatory signals from the...
EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking
Mills, Ian G., Praefcke, Gerrit J.K., Vallis, Yvonne, Peter, Brian J., Olesen, Lene E., Gallop, Jennifer L., ...
EpsinR is a clathrin-coated vesicle (CCV) enriched 70-kD protein that binds to phosphatidylinositol-4-phosphate, clathrin, and the gamma appendage domain of the adaptor protein complex 1 (AP1). In...