Chen, Clark, Merrill, Bradley J., Lau, Patrick J., Holm, Connie, Kolodner, Richard D.
To understand the role of POL30 in mutation suppression, 11 Saccharomyces cerevisiae pol30 mutator mutants were characterized. These mutants were grouped based on their mutagenic defects. Many pol30...
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Merrill, Bradley J., Gat, Uri, DasGupta, Ramanuj, Fuchs, Elaine
In skin, multipotent stem cells generate the keratinocytes of the epidermis, sebaceous gland, and hair follicles. In this paper, we show that Tcf3 and Lef1 control these differentiation lineages. In...
Chen, Clark, Merrill, Bradley J., Lau, Patrick J., Holm, Connie, Kolodner, Richard D.
To understand the role of POL30 in mutation suppression, 11 Saccharomyces cerevisiae pol30 mutator mutants were characterized. These mutants were grouped based on their mutagenic defects. Many pol30...
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Merrill, Bradley J., Gat, Uri, DasGupta, Ramanuj, Fuchs, Elaine
In skin, multipotent stem cells generate the keratinocytes of the epidermis, sebaceous gland, and hair follicles. In this paper, we show that Tcf3 and Lef1 control these differentiation lineages. In...
Repression of Nanog Gene Transcription by Tcf3 Limits Embryonic Stem Cell Self-Renewalâ–¿
Pereira, Laura, Yi, Fei, Merrill, Bradley J.
The dual function of stem cells requires them not only to form new stem cells through self-renewal but also to form lineage-committed cells through differentiation. Embryonic stem cells (ESC), which...