DasGupta, Ramanuj, Nybakken, Kent, Booker, Matthew, Mathey-Prevot, Bernard, Gonsalves, Foster, Changkakoty, Binita, ...
Abstract Off-target effects have been demonstrated to be a major source of false-positives in RNA interference (RNAi) high-throughput screens. In this study, we re-assess the previously published...
Minimizing the risk of reporting false positives in large-scale RNAi screens (2006)
Echeverri, Christophe J, Beachy, Philip A, Baum, Buzz, Boutros, Michael, Buchholz, Frank, Chanda, Sumit K, ...
Large-scale RNA interference (RNAi)-based analyses, very much as other 'omic' approaches, have inherent rates of false positives and negatives. The variability in the standards of care applied to...
Mathey-Prevot, Bernard, Baltimore, David
The v-abl and v-src oncogenes encode protein-tyrosine kinases that possess different biological properties in spite of their high degree of amino acid conservation. To correlate functional...
Regulation of expression of a retroviral transforming gene and its cellular homolog. (1983)
Thesis (Ph. D.)--Rockefeller University.
FlyRNAi: the Drosophila RNAi screening center database
Flockhart, Ian, Booker, Matthew, Kiger, Amy, Boutros, Michael, Armknecht, Susan, Ramadan, Nadire, ...
RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21 000 double-stranded RNAs...
FlyRNAi: the Drosophila RNAi screening center database
Flockhart, Ian, Booker, Matthew, Kiger, Amy, Boutros, Michael, Armknecht, Susan, Ramadan, Nadire, ...
RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library of over 21 000 double-stranded RNAs...
Perrimon, Norbert, Mathey-Prevot, Bernard
RNA interference (RNAi) in tissue culture cells has emerged as an excellent methodology for identifying gene functions systematically and in an unbiased manner. Here, we describe how RNAi...
DasGupta, Ramanuj, Nybakken, Kent, Booker, Matthew, Mathey-Prevot, Bernard, Gonsalves, Foster, Changkakoty, Binita, ...
A second generation dsRNA library was used to re-assess factors that influence the outcome of transcriptional reporter-based whole-genome RNAi screens for the Wnt/Wingless (wg) and Hedgehog...