Kleemann, Robert, Verschuren, Lars, Van Erk, Marjan J, Nikolsky, Yuri, Cnubben, Nicole HP, Verheij, Elwin R, ...
Abstract Background Increased dietary cholesterol intake is associated with atherosclerosis. Atherosclerosis development requires a lipid and an inflammatory component. It is unclear where and how...
Personalised nutrition: status and perspectives (2007)
Joost, Hans-Georg, Gibney, Michael J., Cashman, Kevin D., Görman, Ulf, Hesketh, John E., Mueller, Michael, ...
Personalised, genotype-based nutrition is a concept that links genotyping with specific nutritional advice in order to improve the prevention of nutrition-associated, chronic diseases. This review...
Fiehn, Oliver, Kristal, Bruce, Van Ommen, Ben, Sumner, Lloyd W., Sansone, Susanna-Assunta, Taylor, Chris, ...
Metabolite concentrations in cellular systems are very much dependent on the physiological, environmental, and genetic status of an organism and are regarded as the ultimate result of cellular...
Kaput, Jim, Ordovas, José, Ferguson, Lynnette, Van Ommen, Ben, Rodríguez, Raymond, Allen, Lindsay, ...
Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into...
Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells (2004)
Van Erk, Marjan J, Teuling, Eva, Staal, Yvonne CM, Huybers, Sylvie, Van Bladeren, Peter J, Aarts, Jac MMJG, ...
Abstract Background Curcumin is a spice and a coloring food compound with a promising role in colon cancer prevention. Curcumin protects against development of colon tumors in rats treated with a...
Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells
Van Erk, Marjan J, Teuling, Eva, Staal, Yvonne CM, Huybers, Sylvie, Van Bladeren, Peter J, Aarts, Jac MMJG, ...
Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells
Van Erk, Marjan J, Teuling, Eva, Staal, Yvonne CM, Huybers, Sylvie, Van Bladeren, Peter J, Aarts, Jac MMJG, ...
Kleemann, Robert, Verschuren, Lars, Van Erk, Marjan J, Nikolsky, Yuri, Cnubben, Nicole HP, Verheij, Elwin R, ...
With increasing dietary cholesterol intake the liver switches from a mainly resilient to a predominantly inflammatory state, which is associated with early lesion formation.
The challenges for molecular nutrition research 2: quantification of the nutritional phenotype
Van Ommen, Ben, Keijer, Jaap, Kleemann, Robert, Elliott, Ruan, Drevon, Christian A., McArdle, Harry, ...
In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger...
The challenges for molecular nutrition research 1: linking genotype to healthy nutrition
Williams, Christine M., Ordovas, Jose M., Lairon, Dennis, Hesketh, John, Lietz, Georg, Gibney, Mike, ...
Nutrition science finds itself at a major crossroad. On the one hand we can continue the current path, which has resulted in some substantial advances, but also many conflicting messages which impair...