Anton A. Turanov

In silicoidentification of genes involved in selenium metabolism: evidence for a third selenium utilization trait (2008)

Zhang, Yan, Turanov, Anton A, Hatfield, Dolph L, Gladyshev, Vadim N

Abstract Background Selenium (Se) is a trace element that occurs in proteins in the form of selenocysteine (Sec) and in tRNAs in the form of selenouridine (SeU). Selenophosphate synthetase (SelD) is...

Characterization of Alternative Cytosolic Forms and Cellular Targets of Mouse Mitochondrial Thioredoxin Reductase (2006)

Turanov, Anton A., Su, Dan, Gladyshev, Vadim N.

Thioredoxin reductase (TR) and thioredoxin (Trx) define a major cellular redox system that maintains cysteine residues in numerous proteins in the reduced state. Both cytosolic (TR1 and Trx1) and...

Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism (2005)

Biterova, Ekaterina I., Turanov, Anton A., Gladyshev, Vadim N., Barycki, Joseph J.

Thioredoxin reductase (TrxR) is an essential enzyme required for the efficient maintenance of the cellular redox homeostasis, particularly in cancer cells that are sensitive to reactive oxygen...

Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism

Biterova, Ekaterina I., Turanov, Anton A., Gladyshev, Vadim N., Barycki, Joseph J.

Thioredoxin reductase (TrxR) is an essential enzyme required for the efficient maintenance of the cellular redox homeostasis, particularly in cancer cells that are sensitive to reactive oxygen...

Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism

Biterova, Ekaterina I., Turanov, Anton A., Gladyshev, Vadim N., Barycki, Joseph J.

Thioredoxin reductase (TrxR) is an essential enzyme required for the efficient maintenance of the cellular redox homeostasis, particularly in cancer cells that are sensitive to reactive oxygen...

A new strategy for assessing selenoprotein function: siRNA knockdown/knock-in targeting the 3′-UTR

Yoo, Min-Hyuk, Xu, Xue-Ming, Turanov, Anton A., Carlson, Bradley A., Gladyshev, Vadim N., Hatfield, Dolph L.

Selenocysteine insertion into protein in mammalian cells requires RNA elements in the 3′-untranslated regions (3′-UTRs) of selenoprotein genes. The occurrence of these conserved sequences should...

In silico identification of genes involved in selenium metabolism: evidence for a third selenium utilization trait

Zhang, Yan, Turanov, Anton A, Hatfield, Dolph L, Gladyshev, Vadim N