Andrew Dancis

Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae (2005)

Lesuisse, Emmanuel, Knight, Simon, Courel, Maïte, Santos, Renata, Camadro, Jean-Michel, Dancis, Andrew

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants...

Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae (2005)

Lesuisse, Emmanuel, Knight, Simon, Courel, Maïte, Santos, Renata, Camadro, Jean-Michel, Dancis, Andrew

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants...

Iron Acquisition from Transferrin by Candida albicans Depends on the Reductive Pathway. (2005)

Knight, Simon A. B., Vilaire, Gaston, Lesuisse, Emmanuel, Dancis, Andrew

Host-pathogen interactions that alter virulence are influenced by critical nutrients such as iron. In humans, free iron is unavailable, being present only in high-affinity iron binding proteins such...

Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae (2005)

Lesuisse, Emmanuel, Knight, Simon, Courel, Maïte, Santos, Renata, Camadro, Jean-Michel, Dancis, Andrew

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants...

Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis. (2005)

Zhang, Yan, Lyver, Elise, Knight, Simon, Lesuisse, Emmanuel, Dancis, Andrew

Frataxin is a conserved mitochondrial protein implicated in cellular iron metabolism. Deletion of the yeast frataxin homolog (YFH1) was combined with deletions of MRS3 and MRS4, mitochondrial carrier...

Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae (2005)

Lesuisse, Emmanuel, Knight, Simon, Courel, Maïte, Santos, Renata, Camadro, Jean-Michel, Dancis, Andrew

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants...

Mitochondrial-type assembly of FeS centers in the hydrogenosomes of the amitochondriate eukaryote Trichomonas vaginalis

Sutak, Robert, Dolezal, Pavel, Fiumera, Heather L., Hrdy, Ivan, Dancis, Andrew, Delgadillo-Correa, Maria, ...

Mitochondria are the site of assembly of FeS centers of mitochondrial and cytosolic FeS proteins. Various microaerophilic or anaerobic unicellular eukaryotes lack typical mitochondria...

Zinc suppresses the iron-accumulation phenotype of Saccharomyces cerevisiae lacking the yeast frataxin homologue (Yfh1).

Santos, Renata, Dancis, Andrew, Eide, David, Camadro, Jean-Michel, Lesuisse, Emmanuel

Analysis of Saccharomyces cerevisiae cell transcriptome revealed that iron deprivation/supplementation affects genes other than those of the iron regulon (controlled by Aft proteins). Several genes...

Role of YHM1, encoding a mitochondrial carrier protein, in iron distribution of yeast.

Lesuisse, Emmanuel, Lyver, Elise R, Knight, Simon A B, Dancis, Andrew

Mitochondrial carrier proteins are a large protein family, consisting of 35 members in Saccharomyces cerevisiae. Members of this protein family have been shown to transport varied substrates from...

Iron Acquisition from Transferrin by Candida albicans Depends on the Reductive Pathway

Knight, Simon A. B., Vilaire, Gaston, Lesuisse, Emmanuel, Dancis, Andrew

Host-pathogen interactions that alter virulence are influenced by critical nutrients such as iron. In humans, free iron is unavailable, being present only in high-affinity iron binding proteins such...

Genome-Wide Screen for Genes With Effects on Distinct Iron Uptake Activities in Saccharomyces cerevisiae

Lesuisse, Emmanuel, Knight, Simon A. B., Courel, Maïté, Santos, Renata, Camadro, Jean-Michel, Dancis, Andrew

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants...

Mitochondrial-type assembly of FeS centers in the hydrogenosomes of the amitochondriate eukaryote Trichomonas vaginalis

Sutak, Robert, Dolezal, Pavel, Fiumera, Heather L., Hrdy, Ivan, Dancis, Andrew, Delgadillo-Correa, Maria, ...

Mitochondria are the site of assembly of FeS centers of mitochondrial and cytosolic FeS proteins. Various microaerophilic or anaerobic unicellular eukaryotes lack typical mitochondria...

Zinc suppresses the iron-accumulation phenotype of Saccharomyces cerevisiae lacking the yeast frataxin homologue (Yfh1).

Santos, Renata, Dancis, Andrew, Eide, David, Camadro, Jean-Michel, Lesuisse, Emmanuel

Analysis of Saccharomyces cerevisiae cell transcriptome revealed that iron deprivation/supplementation affects genes other than those of the iron regulon (controlled by Aft proteins). Several genes...

Role of YHM1, encoding a mitochondrial carrier protein, in iron distribution of yeast.

Lesuisse, Emmanuel, Lyver, Elise R, Knight, Simon A B, Dancis, Andrew

Mitochondrial carrier proteins are a large protein family, consisting of 35 members in Saccharomyces cerevisiae. Members of this protein family have been shown to transport varied substrates from...

Iron Acquisition from Transferrin by Candida albicans Depends on the Reductive Pathway

Knight, Simon A. B., Vilaire, Gaston, Lesuisse, Emmanuel, Dancis, Andrew

Host-pathogen interactions that alter virulence are influenced by critical nutrients such as iron. In humans, free iron is unavailable, being present only in high-affinity iron binding proteins such...

Genome-Wide Screen for Genes With Effects on Distinct Iron Uptake Activities in Saccharomyces cerevisiae

Lesuisse, Emmanuel, Knight, Simon A. B., Courel, Maïté, Santos, Renata, Camadro, Jean-Michel, Dancis, Andrew

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants...

GTP in the mitochondrial matrix plays a crucial role in organellar iron homoeostasis1

Gordon, Donna M., Lyver, Elise R., Lesuisse, Emmanuel, Dancis, Andrew, Pain, Debkumar

Mitochondria are the major site of cellular iron utilization for the synthesis of essential cofactors such as iron–sulfur clusters and haem. In the present study, we provide evidence that GTP in...

Frataxin, a Conserved Mitochondrial Protein, in the Hydrogenosome of Trichomonas vaginalis▿

Dolezal, Pavel, Dancis, Andrew, Lesuisse, Emmanuel, Sutak, Róbert, Hrdý, Ivan, Embley, T. Martin, ...

Recent data suggest that frataxin plays a key role in eukaryote cellular iron metabolism, particularly in mitochondrial heme and iron-sulfur (FeS) cluster biosynthesis. We have now identified a...

Hematopoietic Expression of Hoxb4 Is Regulated in Normal and Leukemic Stem Cells through Transcriptional Activation of the Hoxb4 Promoter by Upstream Stimulating Factor (Usf)-1 and Usf-2

Giannola, Diane M., Shlomchik, Warren D., Jegathesan, Mithila, Liebowitz, David, Abrams, Charles S., Kadesch, Tom, ...

The homeobox genes encode a family of transcription factors that regulate development and postnatal tissue homeostasis. Since HOXB4 plays a key role in regulating the balance between hematopoietic...