Andrea Rosner

AML1 deletion in adult mice causes splenomegaly and lymphomas (2006)

Putz, Gabriele, Rosner, Andrea, Nuesslein, Ina, Schmitz, Nicole, Buchholz, Frank

AML1 (RUNX1) encodes a DNA-binding subunit of the CBF transcription factor family and is required for the establishment of definitive hematopoiesis. AML1 is one of the most frequently mutated genes...

Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin (2004)

Jessen, Katayoun, Liu, Stephenie Y, Tepper, Clifford G, Karrim, Juliana, McGoldrick, Erik T, Rosner, Andrea, ...

Abstract Introduction In order to study metastatic disease, we employed the use of two related polyomavirus middle T transgenic mouse tumor transplant models of mammary carcinoma (termed Met and Db)...

Acceleration of Mouse Mammary Tumor Virus-Induced Murine Mammary Tumorigenesis by a p53172H Transgene: Influence of FVB Background on Tumor Latency and Identification of Novel Sites of Proviral Insertion

Chatterjee, Gouri, Rosner, Andrea, Han, Yi, Zelazny, Edward T., Li, Baolin, Cardiff, Robert D., ...

We previously showed that a mammary-specific dominant-negative p53 transgene (WAP-p53172H) could accelerate ErbB2-induced mammary tumorigenesis in mice, but was not tumorigenic on its own. To...

Pathway Pathology : Histological Differences Between ErbB/Ras and Wnt Pathway Transgenic Mammary Tumors

Rosner, Andrea, Miyoshi, Keiko, Landesman-Bollag, Esther, Xu, Xin, Seldin, David C., Moser, Amy R., ...

To study phenotype-genotype correlations, ErbB/Ras pathway tumors (transgenic for ErbB2, c-Neu, mutants of c-Neu, polyomavirus middle T antigene (PyV-mT), Ras, and bi-transgenic for ErbB2/Neu with...