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LongSAGE profiling of nine human embryonic stem cell lines (2007)

Hirst, Martin,
Delaney, Allen,
Rogers, Sean A,
Schnerch, Angelique,
Persaud, Deryck R,
O'Connor, Michael D,
Zeng, Thomas,
Moksa, Michelle,
Fichter, Keith,
Mah, Diana,
Go, Anne,
Morin, Ryan D,
Baross, Agnes,
Zhao, Yongjun,
Khattra, Jaswinder,
Prabhu, Anna-Liisa,
Pandoh, Pawan,
McDonald, Helen,
Asano, Jennifer,
Dhalla, Noreen,
Ma, Kevin,
Lee, Stephanie,
Ally, Adrian,
Chahal, Neil,
Menzies, Stephanie,
Siddiqui, Asim,
Holt, Robert,
Jones, Steven,
Gerhard, Daniela S,
Thomson, James A,
Eaves, Connie J,
Marra, Marco A

Abstract

Abstract To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state.

Publication details

Download	http://genomebiology.com/2007/8/6/R113
Publisher	BioMed Central Ltd.
Repository	BioMed Central (United Kingdom)
Type	Method
Language	Englisch